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Published on: July 6, 2017

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Smartphone-Detected Physiologic Photoleukocoria With Visible Optic Nerve Details

Elizabeth Ransone1, Carolyn May2, Evan Silverstein2

  • 1Virginia Commonwealth University School of Medicine, Richmond, Virginia.

Pediatrics
|March 12, 2025
PubMed

Insights

Smartphone photos revealed leukocoria, an eye’s white reflex, in two children. Further review of these images showed optic nerve details, ruling out serious ocular conditions like retinoblastoma.

Area of Science:

  • Pediatric Ophthalmology
  • Ocular Imaging
  • Diagnostic Ophthalmology

Background:

  • Leukocoria, or a white pupillary reflex, can be an early sign of serious pediatric eye conditions.
  • Smartphone photography is increasingly used for documenting and sharing visual information.
  • Early detection of ocular abnormalities in children is crucial for timely intervention.

Purpose of the Study:

  • To evaluate the diagnostic utility of smartphone-captured photographs in pediatric leukocoria cases.
  • To determine if detailed optic nerve examination is possible from home-submitted photographs.
  • To assess the role of incidental smartphone findings in pediatric ophthalmology referrals.

Main Methods:

  • Two pediatric patients presented with leukocoria noted on family-taken smartphone photos.
  • Comprehensive ophthalmologic examinations were performed, including dilated fundus evaluations.
  • Retrospective analysis of the original smartphone photographs was conducted to assess image quality and content.

Main Results:

  • Ophthalmologic examinations confirmed normal visual acuity and no signs of retinoblastoma or other ocular pathology.
  • Detailed review of the smartphone images revealed discernible optic nerve details in the affected eyes.
  • The leukocoria noted in the photographs did not correlate with significant underlying ocular abnormalities upon clinical examination.

Conclusions:

  • Smartphone photographs can provide valuable preliminary information in pediatric ophthalmology referrals.
  • Careful review of home photographs may aid in identifying subtle optic nerve features.
  • In these cases, smartphone-detected leukocoria was a benign finding, reassuring for parents and clinicians.