Esophageal Siderosis: An Unusual Complication of Oral Iron Therapy

Iron is the most common nutritional deficiency encountered in the United States, with over 15% of Americans using some form of daily oral iron supplementation. Although commonly associated with minor gastrointestinal side effects, severe gastrointestinal complications are rare. Direct cytotoxic mucosal damage and subsequent ulcer formation have rarely been reported. Among reported cases, most are found in the stomach with extragastric manifestations of siderosis being less commonly described. We report a rare case of esophageal siderosis related to oral iron supplementation.