Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Pinching-off of Coated Vesicles01:32

Pinching-off of Coated Vesicles

3.1K
Vesicle budding is orchestrated by distinct cytosolic proteins such as adaptor proteins, coat proteins, and GTPases. To initiate vesicle budding, membrane-bending proteins containing crescent-shaped BAR domains bind to the lipid heads in the bilayer and distort the membrane to form a protein-coated vesicle bud. Adaptors proteins such as AP2 for clathrin-coated vesicles can nucleate on the deformed membrane. Finally, coat proteins such as clathrin or COPI and COPII assemble into a coat forming...
3.1K
Mechanism of Lamellipodia Formation01:31

Mechanism of Lamellipodia Formation

2.5K
Cells migrating in response to external stimuli form lamellipodia, which are thin membrane protrusions supported by a mesh of linked, branched, or unbranched actin filaments. These actin filaments interact with myosin motor proteins, creating the dynamic actomyosin complex within the cytoskeleton. Contractility, or the ability to generate contractile stress, is inherent to the actomyosin complex. It helps cells detect the stiffness of the surrounding ECM and exert contractile force for...
2.5K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Hydrophobicity Does Not Affect Water Slip: Insights from Slip Length Mapping.

Nano letters·2026
Same author

Assessing PFAS fingerprints and precursor burden in AFFF-impacted waters and sediments: An operational screening framework.

Water research·2026
Same author

Dual-stage Healing Mechanism of Dynamic PDMS Vitrimer Thin Films.

Nano letters·2026
Same author

Scalable Photothermal Superhydrophobic Deicing Coating with Mechanochemical-Thermal Robustness.

ACS applied materials & interfaces·2025
Same author

<i>In Situ</i> X-ray Microscopy Unraveling the Onset of Salt Creeping at a Single-Crystal Level.

Langmuir : the ACS journal of surfaces and colloids·2025
Same author

Target and suspect screening of per- and polyfluoroalkyl substances (PFASs) in consumer products using ion mobility separation high resolution mass spectrometry (IMS-HRMS).

Environmental pollution (Barking, Essex : 1987)·2025

Related Experiment Video

Updated: May 22, 2025

Taking Advantage of Reduced Droplet-surface Interaction to Optimize Transport of Bioanalytes in Digital Microfluidics
07:57

Taking Advantage of Reduced Droplet-surface Interaction to Optimize Transport of Bioanalytes in Digital Microfluidics

Published on: November 10, 2014

7.8K

Pinning-Induced Microdroplet Self-Transport.

Hyeongyun Cha1,2,3, Moon-Kyung Kim1, Ho Chan Chang1

  • 1Department of Mechanical Science and Engineering, University of Illinois Urbana-Champaign, Urbana, Illinois 61801, United States.

ACS Nano
|March 13, 2025
PubMed
Summary

Surface defects can cause microdroplets to stick. However, designed surface heterogeneity enables self-transport of microdroplets without external forces, utilizing pinning effects for spontaneous motion.

Keywords:
condensationdropletevaporationhydrophobic surfacenanostructureself-transport

More Related Videos

Capillary-based Centrifugal Microfluidic Device for Size-controllable Formation of Monodisperse Microdroplets
08:20

Capillary-based Centrifugal Microfluidic Device for Size-controllable Formation of Monodisperse Microdroplets

Published on: February 22, 2016

10.3K
High Speed Droplet-based Delivery System for Passive Pumping in Microfluidic Devices
10:22

High Speed Droplet-based Delivery System for Passive Pumping in Microfluidic Devices

Published on: September 2, 2009

13.7K

Related Experiment Videos

Last Updated: May 22, 2025

Taking Advantage of Reduced Droplet-surface Interaction to Optimize Transport of Bioanalytes in Digital Microfluidics
07:57

Taking Advantage of Reduced Droplet-surface Interaction to Optimize Transport of Bioanalytes in Digital Microfluidics

Published on: November 10, 2014

7.8K
Capillary-based Centrifugal Microfluidic Device for Size-controllable Formation of Monodisperse Microdroplets
08:20

Capillary-based Centrifugal Microfluidic Device for Size-controllable Formation of Monodisperse Microdroplets

Published on: February 22, 2016

10.3K
High Speed Droplet-based Delivery System for Passive Pumping in Microfluidic Devices
10:22

High Speed Droplet-based Delivery System for Passive Pumping in Microfluidic Devices

Published on: September 2, 2009

13.7K

Area of Science:

  • Physics
  • Materials Science
  • Surface Science

Background:

  • Microdroplets adhere to solid surfaces due to unavoidable micro- and nanoscale defects.
  • Surface and potential energy gradients or external energy are typically required to initiate droplet motion.

Purpose of the Study:

  • To demonstrate that designed surface heterogeneity can induce spontaneous microdroplet self-transport.
  • To explore an alternative mechanism for droplet mobility without external forces or anisotropy.

Main Methods:

  • Investigating the effect of topological defects on microdroplet behavior.
  • Analyzing contact line pinning and its role in generating asymmetry.

Main Results:

  • Microdroplets exhibit spontaneous motion over distances significantly larger than their radius (10-20 times).
  • Contact line pinning at topological defects leads to contact angle asymmetry, driving motion.
  • Self-transport occurs without external energy input or inherent surface anisotropy.

Conclusions:

  • Surface heterogeneity, when properly designed, can be leveraged for passive droplet mobility.
  • This finding offers a novel approach for controlling droplet movement in applications requiring passive transport.