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Updated: May 22, 2025

A Novel Digital Platform for a Monitored Home-based Cardiac Rehabilitation Program
Published on: April 19, 2019
Exercise Training and Rehabilitation in Cardiac Amyloidosis (ERICA) Study: Rationale and Design
Alberto M Marra1, Giuseppe Palmiero2, Mariangela Losi3
1Department of Translational Medical Sciences, "Federico II" University of Naples, "Federico II" University Hospital and School of Medicine, Building N. 18, First Floor, Via Pansini 5, Naples I-81031, Italy; A.O.U. "Federico II" University Hospital, Naples, Italy.
Abstract:
Notwithstanding the dramatic improvement associated with Tafamidis in Heart Failure due to wild-type transthyretin cardiac amyloidosis (ATTRwt-CA), the effect of exercise training on ATTRwt-CA remains unexplored. We hereby present rationale and design of the Exercise training and Rehabilitation in Cardiac Amyloidosis study. This interventional, controlled study will randomize ATTRwt-CA patients into a control group and a training group. Primary endpoint will be the distance obtained at the 6-min walk test. Quality-of-life, peak oxygen consumption, left and right heart architecture and function, and natriuretic peptides will be secondary endpoints.
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