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4D printing polymeric biomaterials for adaptive tissue regeneration.
Zhe Wang1,2, Duo Ma2,3, Juan Liu2,3
1Department of Burn and Plastic Surgery, Shenzhen Longhua District Central Hospital, Shenzhen, 518110, China.
Bioactive Materials
|March 14, 2025
Summary
4D printing uses smart polymeric biomaterials that change shape with stimuli, overcoming limitations of static 3D printed structures for tissue regeneration applications.
Area of Science:
- Biomaterials Science
- Tissue Engineering
- Additive Manufacturing
Background:
- Traditional 3D-printed structures are static and have limitations.
- 4D printing polymeric biomaterials offer dynamic, stimulus-responsive capabilities.
- These materials can adapt their morphology and performance.
Purpose of the Study:
- To provide a systematic overview of 4D printing polymeric biomaterials for tissue regeneration.
- To discuss the principles, smart properties, and deformation mechanisms of these materials.
- To explore applications and future prospects in tissue regeneration.
Main Methods:
- Systematic review of 4D printing polymeric biomaterials.
- Discussion of smart properties and deformation mechanisms.
- Introduction of material design, preparation, and application.
Main Results:
- 4D printing enables dynamic, responsive biomaterials.
- Various polymeric biomaterials and composites are suitable for 4D printing.
- These materials show promise for tissue regeneration applications.
Conclusions:
- 4D printing polymeric biomaterials offer advantages over static structures.
- Further research can enhance their efficiency and convenience in tissue regeneration.
- This field holds innovative potential for regenerative medicine.
