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    Area of Science:

    • Optical Physics
    • Biomedical Optics

    Background:

    • Space-time wave packets exhibit diffraction-free propagation, attracting significant interest in optical physics.
    • This diffraction-free property holds potential for biomedical optics applications.

    Purpose of the Study:

    • To experimentally and numerically demonstrate the diffraction-resistant properties of space-time light sheets.
    • To compare the propagation characteristics of space-time light sheets with Airy, Bessel, and Gaussian light sheets.

    Main Methods:

    • Synthesizing a 10-µm-thick space-time light sheet by tuning the spectral tilt angle of a light cone.
    • Experimentally and numerically measuring the width of space-time, Airy, Bessel, and Gaussian light sheets over a 2 mm propagation distance.

    Main Results:

    • The space-time light sheet maintained its 10-µm width over 2 mm of free-space propagation without a focusing lens.
    • Airy, Bessel, and Gaussian light sheets of comparable initial thickness diverged significantly, becoming 4.5× to 10× wider over the same distance.

    Conclusions:

    • Space-time light sheets demonstrate superior diffraction resistance compared to conventional light sheet types.
    • These findings suggest space-time light sheets are a promising tool for achieving extended depth-of-focus in light sheet microscopy.