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Alternate encoder and dual decoder CNN-Transformer networks for medical image segmentation
Lin Zhang1, Xinyu Guo2, Hongkun Sun3
1Zhejiang Hospital of Integrated Traditional Chinese and Western Medicine, Hangzhou, 310003, China.
Scientific Reports
|March 15, 2025
Summary
This study introduces AD2Former, a novel CNN-Transformer network for medical image segmentation. It effectively combines local and global features to improve lesion extraction accuracy, outperforming previous models.
Area of Science:
- Medical Image Analysis
- Computer Vision
- Deep Learning
Background:
- Accurate medical image segmentation is crucial but challenging.
- Convolutional Neural Networks (CNNs) and Transformers excel at local and global feature extraction, respectively.
- Integrating CNNs and Transformers is key for medical image segmentation, but challenges remain in fully utilizing local and global features.
Purpose of the Study:
- To propose a novel CNN-Transformer network, AD2Former, for enhanced medical image segmentation.
- To address limitations in extracting effective local and global features in previous models.
- To improve the segmentation of lesions with unique tissue characteristics and fuzzy boundaries.
Main Methods:
- Developed AD2Former, an encoder-decoder network with an alternating learning encoder and a dual-decoder architecture.
- The alternating learning encoder facilitates real-time interaction between local and global information.
- The dual-decoder architecture employs independent decoding branches with a channel attention module for feature fusion.
Main Results:
- AD2Former demonstrated a strong ability to capture target regions and fuzzy boundaries in medical images.
- Experiments on multi-organ and skin lesion segmentation datasets confirmed the model's effectiveness.
- The proposed designs, alternating learning encoder and dual decoder, significantly contributed to performance gains.
Conclusions:
- AD2Former effectively integrates local and global feature extraction for superior medical image segmentation.
- The novel architecture addresses key challenges in segmenting complex lesion tissues.
- The model shows significant potential for improving diagnostic accuracy in medical imaging applications.

