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Related Concept Videos

CNS Stimulants: Psychedelic Agents01:22

CNS Stimulants: Psychedelic Agents

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Hallucinogens, also known as psychedelic drugs, are a class of substances known for their ability to alter perception, cognition, and emotions. Despite their profound effects on the mind, these drugs are non-addictive, setting them apart from many other abused substances. The mechanism of action of these drugs lies in their impact on the 5-HT2A receptor in the brain. Upon activation, this receptor couples to Gq-type G proteins, triggering a cascade that releases intracellular calcium. This...
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Drug Abuse and Addiction: Pharmacological Phenomena01:15

Drug Abuse and Addiction: Pharmacological Phenomena

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Drug dependence, abuse, and addiction are complex phenomena that can precipitate various abnormal states. Physical dependence refers to a state of pharmacological adaptation to a drug. This adaptation often results in tolerance—a reduced response to the drug after repeated administrations. When the drug use is abruptly stopped, withdrawal symptoms occur due to the body's need to readjust from the pharmacologically induced imbalance. However, tolerance and withdrawal symptoms do not...
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Hallucinogens and Psychedelics01:27

Hallucinogens and Psychedelics

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Hallucinogens are psychoactive substances that profoundly alter perceptual experiences, generating unreal visual and sensory images. Often referred to as psychedelic drugs — a term derived from the Greek words "psyche" (mind) and "delos" (revealing) — these substances include marijuana and lysergic acid diethylamide (LSD), among others. These drugs vary in intensity and effects.
Marijuana, derived from the dried leaves and flowers of the hemp plant, contains...
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An Overview of Psychoactive Drugs01:28

An Overview of Psychoactive Drugs

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Psychoactive drugs impact brain function, influencing perception, mood, consciousness, cognition, and behavior. These substances are grouped based on their effects and the mechanisms by which they act.
Stimulants such as cocaine, amphetamines, and nicotine enhance brain activity, leading to increased alertness, attention, and energy. These drugs typically raise heart rate, blood pressure, and body temperature. While they can induce feelings of euphoria, their misuse can result in severe health...
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Substance Use Disorders Affecting Sleep01:24

Substance Use Disorders Affecting Sleep

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Substance use disorders involve a pattern of using drugs more extensively than intended and continuing use despite harmful consequences. This includes legal substances like alcohol and nicotine, as well as illegal drugs. These disorders often involve both physical and psychological dependence, reflecting compulsive use of substances that significantly alter thoughts, feelings, and behaviors, contributing to a major public health issue.
Understanding the concepts of physical dependence,...
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Drug Dependence01:17

Drug Dependence

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Medications are typically administered to achieve therapeutic effects. Some drugs can modify an individual's mood and perception, frequently resulting in various enjoyable experiences. However, this can result in drug dependency, a condition marked by continuous drug use despite potential negative consequences. Drug dependency primarily falls into two categories: psychological and physical dependence. Psychological dependence occurs when the pleasurable feelings induced by the drug...
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Psychedelic Use and Behavioral Addictions.

Trey Brasher1, David Rosen2, Marcello Spinella3

  • 1Pharmacology and Toxicology Graduate Group, University of California, Davis, USA.

Journal of Psychoactive Drugs
|March 15, 2025
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Summary
This summary is machine-generated.

Psychedelic use was linked to lower behavioral addiction symptoms, including problem gambling and compulsive buying. These findings suggest psychedelics may offer a novel therapeutic avenue for behavioral addictions.

Keywords:
Psychedelicsaddictionbehavioral addictionnaturalisticself-report survey

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Area of Science:

  • Psychiatry
  • Neuroscience
  • Psychology

Background:

  • Clinical trials show classic psychedelics' potential for depression and anxiety.
  • Pre-clinical and clinical research suggests psychedelics may help with substance use disorders.
  • Behavioral addictions share features with substance addictions, indicating potential for psychedelic treatment.

Purpose of the Study:

  • To examine self-reported symptoms of behavioral addictions in a community sample.
  • To assess the relationship between well-being, behavioral addiction symptoms, and psychedelic use.
  • To explore the potential of psychedelics in treating behavioral addictions.

Main Methods:

  • Surveyed 1107 individuals on behavioral addiction symptoms (gambling, sexual, buying, eating disorders).
  • Assessed well-being measures (self-transcendence, personal growth, depression/anxiety).
  • Utilized principal components analysis and multiple regression analyses to analyze data, controlling for demographics and other drug use.

Main Results:

  • Significant positive correlations found among well-being measures and among behavioral addiction symptoms.
  • Inverse correlations observed between well-being and behavioral addictions.
  • Psychedelic users reported greater well-being and lower behavioral addiction symptoms compared to non-users.
  • Psychedelic use uniquely predicted lower behavioral addiction scores, while stimulant, alcohol, and nicotine vaping predicted higher scores.

Conclusions:

  • Findings suggest psychedelics may aid in treating behavioral addictions.
  • Psychedelic use is associated with improved well-being and reduced behavioral addiction symptoms.
  • A controlled pilot study or clinical trial is warranted to further explore this therapeutic potential.