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Mania resulting from brain stem tumor.

D B Greenberg, G L Brown

    The Journal of Nervous and Mental Disease
    |July 1, 1985
    PubMed
    Summary
    This summary is machine-generated.

    A rare case shows manic behavior can signal a brain tumor. This suggests considering cancer when mania appears without a history of mood disorders.

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    Area of Science:

    • Neuro-oncology
    • Psychiatry
    • Neurology

    Background:

    • Recurrent affective illness, like bipolar disorder, often has a genetic basis.
    • Mania or hypomania are typically associated with mood disorders, not occult neoplasms.
    • The link between neoplastic disease and manic symptoms is not well-established.

    Observation:

    • A 55-year-old man presented with manic behavior.
    • The patient had no personal or family history of affective disease.
    • Diagnostic workup revealed a metastatic mesencephalic tumor.

    Findings:

    • The patient's manic episode was the presenting symptom leading to the diagnosis of a brain tumor.
    • This case highlights an unusual presentation of a mesencephalic tumor.

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    Implications:

    • Clinicians should consider the possibility of an underlying neoplasm in patients presenting with new-onset mania, especially in the absence of a prior psychiatric history.
    • This case broadens the differential diagnosis for mania and underscores the importance of thorough medical evaluation.