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Obsessive-compulsive disorder in the World Mental Health surveys
Dan J Stein1, Ayelet Meron Ruscio2, Yasmin Altwaijri3
1University of Cape Town.
Research Square
|March 17, 2025
Summary
Obsessive-compulsive disorder (OCD) affects 4.1% of adults globally, often starting in early adulthood and frequently remaining untreated, especially in low-income countries. Early diagnosis and treatment are crucial for this prevalent mental health condition.
Area of Science:
- Psychiatry
- Epidemiology
- Global Mental Health
Background:
- Obsessive-compulsive disorder (OCD) is recognized as a significant mental health condition, yet cross-national data, particularly from low- and middle-income countries (LMICs), are limited.
- Existing national surveys indicate OCD's prevalence and impairing nature, highlighting the need for broader international research.
Purpose of the Study:
- To characterize the onset, course, severity, and treatment of OCD across diverse countries using data from the World Mental Health surveys.
- To investigate predictors of OCD onset, persistence, severity, and treatment, including socio-demographic variables and prior mental disorders.
Main Methods:
- Utilized data from general population surveys in 10 countries, employing a consistent research protocol and face-to-face interviews with 26,136 adults.
- Assessed lifetime and 12-month prevalence, age of onset, persistence, severity (using Yale-Brown Obsessive-Compulsive Scale), and treatment rates for DSM-IV OCD.
- Examined socio-demographic factors and preceding mental disorders as potential predictors.
Main Results:
- The combined lifetime prevalence of OCD across 10 countries was 4.1%, with a 12-month prevalence of 3.0%, indicating a persistent course.
- OCD typically emerges in adolescence or early adulthood (over 80% of cases), with most community cases being mild to moderate.
- Treatment rates were low overall (19.8%), significantly lower in LMICs (7.0%) compared to high-income countries (HICs) (40.5%).
Conclusions:
- Cross-national data reveal OCD as a prevalent and persistent disorder, often beginning early in life and frequently undertreated, particularly in LMICs.
- Emphasizes the public health significance of OCD and the need for early diagnosis, comprehensive comorbidity assessment, and improved treatment access.
- Highlights distinct socio-demographic and psychopathological risk factors for OCD onset, persistence, severity, and treatment across different countries.
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