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Skin Cancer01:30

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Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
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Related Experiment Video

Updated: May 2, 2026

Endoscopic Endonasal Trans-sphenoidal Approach: Minimally Invasive Surgery for Pituitary Adenomas
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Systematic Review Comparing Open Versus Minimally Invasive Surgical Management of Intradural Extramedullary Tumours

Asfand Baig Mirza1,2,3, Ariadni Georgiannakis2,4, Feras Fayez2,5

  • 1Department of Neurosurgery, Queen's Hospital Romford, Barking, Havering and Redbridge NHS Trust, Essex RM7 0AG, UK.

Journal of Clinical Medicine
|March 17, 2025
PubMed
Summary

Minimally invasive surgery for intradural extramedullary (IDEM) spinal tumors offers comparable or better outcomes than open surgery. This approach shows promise for improved patient recovery and reduced complications.

Keywords:
IDEMlaminectomyminimally invasivesystematic review

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Area of Science:

  • Neurosurgery
  • Spinal Surgery
  • Oncology

Background:

  • Intradural extramedullary (IDEM) spinal tumors are uncommon, typically benign.
  • Gross total resection (GTR) is the primary treatment goal.
  • Minimally invasive techniques are increasingly explored for achieving GTR.

Purpose of the Study:

  • To review current surgical management options for IDEM tumors.
  • To compare outcomes between open and minimally invasive surgical techniques.
  • To evaluate the efficacy and safety of different surgical approaches for IDEM tumors.

Main Methods:

  • Systematic literature search conducted in December 2024.
  • Inclusion of studies reporting surgical treatment for IDEM tumors.
  • Assessment of GTR, postoperative neurological function, and complications.

Main Results:

  • Data from 4695 IDEM cases (3495 open, 750 minimally invasive).
  • Mean GTR exceeded 90% across both approaches.
  • Minimally invasive surgery demonstrated lower complication rates (11.1% vs. 14.3%), improved functional outcomes (McCormick score change -1.30 vs. -0.64), and lower recurrence (1.4% vs. 10.0%).

Conclusions:

  • Open surgery provides acceptable resection and neurological improvement.
  • Minimally invasive surgery shows potential for superior resection rates and fewer complications.
  • Minimally invasive surgery may lead to reduced costs and shorter hospital stays.