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Updated: May 21, 2025

Author Spotlight: Anterior HR-OCT as a Non-Invasive Tool for Characterizing Ocular Surface Squamous Neoplasia
Published on: August 9, 2024
Update in the Diagnosis and Management of Ocular Surface Squamous Neoplasia (OSSN)
Michael Tsatsos1, Chryseis Delimitrou1, Ioannis Tsinopoulos1
12nd Ophthalmology Department, Aristotle University of Thessaloniki, Papageorgiou Hospital, Ag Pavlou 76, 564 29 Thessaloniki, Greece.
Abstract:
Ocular surface squamous neoplasia (OSSN) includes a variety of ocular surface tumors ranging from mild epithelial dysplasia to invasive squamous cell carcinoma. OSSN is one of the most frequent non-pigmented malignancies of the ocular surface. Debate persists between surgical excision and medical management concerning the optimal regimen for OSSN treatment, with surgical excision continuing to be the recognized standard of care in contemporary medicine. Medical and conservative therapy techniques have advanced significantly in recent years, leading to widespread use in everyday ophthalmology practice. This study aims to look into the efficacy of current treatment options for conjunctival squamous cell carcinoma and to evaluate the available evidence for the most up-to-date approach for the management of the disease.
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