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Nadia Romdhane1, Dorra Chiboub1, Amira Khaldi1

  • 1ENT and Head and Neck Surgery Department, Habib Thamer Hospital, University of Tunis El Manar, Faculty of Medicine of Tunis, Tunisia.

La Tunisie Medicale
|March 17, 2025
PubMed
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Non-invasive follicular thyroid neoplasms with papillary-like nuclear features (NIFTP) are controversial. This study details their characteristics and management, finding no recurrences after surgery, emphasizing strict diagnostic criteria.

Area of Science:

  • Endocrinology
  • Surgical Pathology
  • Oncology

Context:

  • Non-invasive follicular thyroid neoplasms with papillary-like nuclear features (NIFTP) present diagnostic and therapeutic challenges.
  • Histological criteria and management strategies for NIFTP remain subjects of debate.
  • Accurate classification is crucial for appropriate patient care.

Purpose:

  • To investigate the clinicopathological features of NIFTP.
  • To evaluate the therapeutic management and outcomes for NIFTP patients.
  • To highlight the importance of precise diagnostic criteria.

Summary:

  • A retrospective study analyzed 23 patients with NIFTP, revealing predominantly female patients with incidentally discovered nodules.
  • EUTIRADS III/IV and Bethesda III/IV cytology were common; total thyroidectomy was the primary treatment.
Keywords:
NIFTPThyroid tumorfine needle aspirationsurgeryultrasound

Related Experiment Videos

  • No locoregional or distant recurrence was observed during follow-up, supporting strict adherence to diagnostic criteria.

    • Impact:

    • Provides insights into the clinical behavior of NIFTP.
    • Informs surgical and pathological decision-making for NIFTP cases.
    • Reinforces the significance of meticulous histopathological evaluation for NIFTP diagnosis and patient management.