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The Retinoblastoma Gene

The Retinoblastoma Gene

Tumor suppressor genes are normal genes that can slow down cell division, repair DNA mistakes, or program the cells for apoptosis in case of irreparable damage. Hence, they play an essential role in preventing the proliferation of damaged cells.
The first-ever tumor suppressor gene called Rb was identified in retinoblastoma - a rare eye tumor in children. In inherited forms of the disease, a child inherits one defective copy of the Rb gene, which predisposes them to retinoblastoma. However,...

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Related Experiment Video

Updated: May 21, 2025

Establishment and Propagation of Human Retinoblastoma Tumors in Immune Deficient Mice

Establishment and Propagation of Human Retinoblastoma Tumors in Immune Deficient Mice

Published on: August 4, 2011

Correction: Presumed Ectopic Trilateral Retinoblastoma: Case Report

Cecilia Clara Maria Mattavelli¹, Meriam Koob², Maja Beck-Popovic³

¹Pediatric Ocular Oncology, Jules-Gonin Eye Hospital, Lausanne, Switzerland.

Klinische Monatsblatter Fur Augenheilkunde

|March 17, 2025

Summary

No abstract available in PubMed .

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