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Related Concept Videos

Endocarditis I: Introduction01:25

Endocarditis I: Introduction

Introduction:Endocarditis is the infection of the endocardium, the inner lining of the heart and its valves. When the heart muscle is involved, the condition is termed myocarditis, while an infection of the outer lining is called pericarditis. Infective endocarditis (IE) primarily affects the endocardium, where pathogens adhere to the valves or lining, forming vegetation that can lead to severe complications. Infective endocarditis occurs when microorganisms, usually bacteria from other body...
Endocarditis II: Clinical Features of Infective Endocarditis01:25

Endocarditis II: Clinical Features of Infective Endocarditis

Endocarditis can present various clinical features depending on the causative organism and the patient's underlying health conditions. Initially, the clinical features of infective endocarditis develop gradually, presenting with nonspecific symptoms that can be easily mistaken for other illnesses.General SymptomsEarly symptoms of infective endocarditis are fever, chills, weakness, malaise, fatigue, and weight loss. These symptoms reflect the systemic nature of the infection and the body's...
Endocarditis III: Medical Management01:18

Endocarditis III: Medical Management

Infective endocarditis management involves a multifaceted approach encompassing infection prevention, lifestyle modifications, pharmacological therapy, and surgical management.Infection Prevention:Hand Hygiene: Thorough handwashing is crucial to prevent the spread of infection. Hand hygiene should be performed regularly, especially before and after using the restroom.Oral Hygiene: Good oral hygiene is essential. It includes brushing teeth immediately after waking up and before bed, flossing...
Endocarditis IV: Nursing Management01:29

Endocarditis IV: Nursing Management

Infective endocarditis (IE) is a chronic infection of the heart's endocardium, primarily affecting the heart valves. A detailed nursing assessment for a patient with IE involves collecting subjective and objective data to ensure an accurate diagnosis and timely intervention.Subjective DataThe nurse gathers information about the patient's symptoms and complaints during the subjective assessment. Patients with infective endocarditis often report non-specific symptoms that can mimic other...

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Related Experiment Video

Updated: May 12, 2026

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The Ross Procedure in Active Infective Endocarditis: A Comparison With Conventional Prostheses.

Hiromu Kehara1, Mohammed Kashem1, Huaqing Zhao2

  • 1Division of Cardiovascular Surgery, Lewis Katz School of Medicine at Temple University, Philadelphia, Pennsylvania.

Annals of Thoracic Surgery Short Reports
|March 18, 2025
PubMed
Summary

The Ross procedure shows promise for infective endocarditis (IE), offering similar short-term outcomes and fewer reoperations compared to conventional aortic valve surgeries. Midterm results suggest it may be a superior option for IE patients.

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Area of Science:

  • Cardiovascular Surgery
  • Infective Diseases
  • Prosthetic Valve Surgery

Background:

  • The Ross procedure is considered for infective endocarditis (IE) due to potential resistance to infection.
  • Limited comparative data exists between the Ross procedure and conventional prostheses in IE patients.

Purpose of the Study:

  • To compare the outcomes of the Ross procedure versus conventional aortic valve surgery in patients with infective endocarditis.
  • To evaluate the efficacy and safety of the Ross procedure in the context of IE.

Main Methods:

  • A retrospective study comparing 25 patients undergoing the Ross procedure for IE (Ross group) with 37 patients undergoing other aortic valve procedures for IE (other group).
  • Data collected on patient demographics, surgical complexity, short-term outcomes, reoperation rates, and composite events.

Main Results:

  • The Ross group had higher rates of intravenous drug use, prosthetic valve endocarditis, and annular abscesses.
  • Despite longer bypass and cross-clamp times, short-term outcomes were similar. The Ross group had significantly lower reoperation rates (4% vs. 16%) and fewer composite events (P = .04).
  • Multivariable analysis identified the Ross procedure as an independent protective factor against composite endpoints (P = .03).

Conclusions:

  • The Ross procedure offers comparable short-term outcomes to other aortic valve procedures in IE patients, despite increased surgical complexity.
  • In the midterm, the Ross procedure demonstrates a lower reoperation rate and significantly fewer composite events, suggesting it may be a favorable option for IE.
  • Long-term follow-up is essential to fully ascertain the benefits of the Ross procedure in infective endocarditis.