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Towards developing brain-computer interfaces for people with Multiple Sclerosis.
John S Russo1, Tim Mahoney1, Kirill Kokorin1,2
1Department of Biomedical Engineering, The University of Melbourne, Melbourne, Australia.
Plos One
|March 18, 2025
Summary
People with Multiple Sclerosis (MS) show interest in Brain-Computer Interface (BCI) technology. User needs for MS-specific BCI development emphasize non-invasive or minimally invasive designs for home use.
Area of Science:
- Neuroscience
- Biomedical Engineering
- Rehabilitation Technology
Background:
- Multiple Sclerosis (MS) causes disabling neurological symptoms, impacting quality of life.
- Existing Brain-Computer Interface (BCI) research inadequately addresses MS-specific needs and home environments.
- There's a need to evaluate user requirements for effective BCI development in MS.
Purpose of the Study:
- To assess user needs and preferences for Brain-Computer Interface (BCI) technology among individuals with Multiple Sclerosis (MS).
- To evaluate the feasibility and user-centric requirements for developing MS-specific BCIs.
- To explore interest in BCI and bionic applications for assisting individuals with MS.
Main Methods:
- An online survey was conducted with individuals diagnosed with Multiple Sclerosis (MS).
- The survey collected data on BCI and bionic application interest, device preferences, and development considerations.
- Data was analyzed to understand preferences in relation to MS symptoms and assistance needs.
Main Results:
- Widespread interest in BCI applications was observed across all stages of MS.
- A preference for non-invasive (n=12) or minimally invasive (n=15) BCIs over carer assistance (n=6) was reported.
- Level of independence did not correlate with a preference for highly invasive BCIs.
Conclusions:
- User-centered design is crucial for developing effective BCIs for individuals with MS.
- Future BCI advancements should consider the unique pathological changes in MS and prioritize home environment integration.
- Developing BCIs tailored to user needs can enhance independence and quality of life for people living with MS.

