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Updated: May 21, 2025

Fluorescence-Based Measurements of Phosphatidylserine/Phosphatidylinositol 4-Phosphate Exchange Between Membranes
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Glycerophospholipids: Roles in Cell Trafficking and Associated Inborn Errors

Foudil Lamari1,2, Francis Rossignol3,4, Grant A Mitchell4

  • 1Metabolic Biochemistry, Neurometabolic and Neurodegenerative Unit - DMU BioGeMH Hôpital Pitié-Salpêtrière, AP-HP. Sorbonne Université, Paris, France.

Journal of Inherited Metabolic Disease
|March 18, 2025
PubMed
Summary

Glycerophospholipids (GPLs) are vital membrane lipids involved in many cell functions. Inborn errors of GPL metabolism cause diverse, often severe, neurologic and retinal diseases, highlighting the need for advanced diagnostics like lipidomics.

Keywords:
Glycerophospholipidbiosynthesiscell traffickinginborn errors of metabolismremodelling

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