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ARTERIOVENOUS FISTULA FOR HEMODIALYSIS IN RELATION TO THE TIMING OF CREATION: ANALYSIS OF KEY FACTORS
Radojica V Stolić1, Mirjana Pajčin2, Vekoslav Mitrović3
1University of Kragujevac, Faculty of Medical Sciences, Department of Internal Medicine, Kragujevac, Serbia.
Acta Clinica Croatica
|March 19, 2025
Summary
Arteriovenous fistula creation timing impacts outcomes. Vein diameter, cholesterol, and LDL predict initial dysfunction, while systolic blood pressure is key for maturation.
Area of Science:
- Nephrology and Vascular Surgery
- Dialysis Access Management
Background:
- Timely creation of arteriovenous fistulas (AVFs) for hemodialysis is crucial but not always feasible.
- Understanding factors influencing AVF functionality and maturation is essential for optimizing patient care.
Purpose of the Study:
- To identify key factors affecting arteriovenous fistula functionality and maturation.
- To analyze these factors in relation to the timing of fistula creation (pre- vs. post-hemodialysis initiation).
Main Methods:
- Retrospective analysis of 1089 patients undergoing AVF creation over fifteen years.
- Comparison of clinical and biochemical parameters between patients with pre- and post-hemodialysis AVF creation.
- Statistical analysis to determine predictive factors for initial dysfunction and maturation.
Main Results:
- Significant differences observed between pre- and post-hemodialysis groups in vein lumen, systolic blood pressure, total cholesterol, HDL, and LDL cholesterol.
- Vein diameter, total cholesterol, and LDL cholesterol were predictive of initial AVF dysfunction.
- Systolic blood pressure emerged as the primary predictor for AVF maturation.
Conclusions:
- Vein diameter, cholesterol levels, and LDL cholesterol are critical predictors of initial arteriovenous fistula dysfunction.
- Maintaining optimal systolic blood pressure is paramount for successful AVF maturation.
- The timing of AVF creation relative to hemodialysis initiation influences key patient parameters.
