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Short-Term Cardiometabolic Response to Mango Intake in Postmenopausal Women.

Roberta R Holt1, Esther Ho1, Xiang Li1

  • 1Department of Nutrition, University of California, Davis, Davis, California, USA.

Journal of the American Nutrition Association
|March 19, 2025
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Summary

Daily mango consumption for two weeks improved cardiometabolic markers, including blood pressure and cholesterol, in overweight postmenopausal women. Mango intake also moderated blood glucose and insulin responses compared to white bread.

Keywords:
Mangoblood pressurecardiometaboliccell adhesion markersmicrovascular functionpostmenopausalpulse pressure

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Area of Science:

  • Nutrition Science
  • Cardiovascular Health
  • Metabolic Health

Background:

  • Mango consumption is linked to better diet quality and reduced blood pressure.
  • Previous studies suggest benefits from 6-8 weeks of daily mango intake.
  • The effects of shorter mango intake periods remain unclear.

Purpose of the Study:

  • To investigate the impact of a two-week mango intake on microvascular function and cardiometabolic markers.
  • To compare outcomes in overweight/obese postmenopausal women to baseline measures.
  • To explore mango's effect on glucose and insulin metabolism compared to white bread.

Main Methods:

  • A two-week intervention with daily mango intake (330g/d) in postmenopausal women.
  • Comparison of cardiometabolic markers and microvascular function to baseline data.
  • A probe study comparing mango to calorically-equivalent white bread.

Main Results:

  • No significant changes in microvascular function were observed.
  • Significant reductions in systolic blood pressure, mean arterial pressure, mean pulse pressure, and fasting cholesterol.
  • Mango intake moderated postprandial glucose and insulin responses compared to white bread.

Conclusions:

  • Two weeks of mango intake can positively impact cardiometabolic risk factors.
  • Mangoes may play a role in moderating glucose absorption and metabolism.
  • Further research with typical consumption amounts and longer durations is recommended.