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Cutaneous abnormalities in uremic patients.

P L Bencini, G Montagnino, A Citterio

    Nephron
    |January 1, 1985
    PubMed
    Summary
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    Dermatological issues like dry skin, itching, infections, and pigmentation changes are common in patients undergoing regular hemodialysis treatment (RHT) and chronic ambulatory peritoneal dialysis (CAPD). Some RHT patients also developed precancerous and cancerous skin lesions.

    Area of Science:

    • Nephrology
    • Dermatology
    • Internal Medicine

    Background:

    • Uremia, a condition of kidney failure, is associated with numerous systemic complications.
    • Dialysis, including regular hemodialysis treatment (RHT) and chronic ambulatory peritoneal dialysis (CAPD), is a life-sustaining therapy for uremic patients.
    • Cutaneous manifestations are frequently observed in patients with chronic kidney disease and those undergoing dialysis.

    Purpose of the Study:

    • To investigate the prevalence and characteristics of dermatological manifestations in patients with uremia undergoing different dialysis modalities.
    • To identify common skin lesions and potential risks associated with long-term dialysis treatment.

    Main Methods:

    • A cohort of 94 uremic patients was studied over a period of up to 20 months.

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  • Patients were divided into two groups: 68 on regular hemodialysis treatment (RHT) and 26 on chronic ambulatory peritoneal dialysis (CAPD).
  • Dermatological examinations were conducted to identify and document cutaneous lesions.

    • Main Results:

    • A high prevalence of skin lesions was observed in both groups: 79% in RHT patients and 76% in CAPD patients.
    • Common dermatological findings included cutaneous xerosis (dry skin), pruritus (itching), infectious manifestations, and disorders of pigmentation.
    • Four patients on RHT exhibited precancerous and cancerous skin manifestations.

    Conclusions:

    • Patients undergoing both RHT and CAPD experience a high incidence of dermatological problems.
    • Xerosis, pruritus, infections, and pigmentation changes are characteristic skin issues in dialysis patients.
    • The occurrence of precancerous and cancerous lesions in a subset of RHT patients highlights the need for vigilant dermatological surveillance in this population.