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Updated: May 21, 2025

In Vivo Multimodal Imaging and Analysis of Mouse Laser-Induced Choroidal Neovascularization Model
Published on: January 21, 2018
NOVEL INTRAOPERATIVE FUNDUS FLUORESCEIN ANGIOGRAPHY REVEALS NEOVASCULARIZATION AT THE SCLEROTOMY SITE IN
1Department of Ophthalmology, Sichuan Provincial People's Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu, China.
Purpose:
The purpose of this study was to report a case of long-term postoperative vitreous hemorrhage of proliferative diabetic retinopathy after pars plana vitrectomy, which is most likely to be associated with neovascularization formed at the incision site of vitrectomy, and to recommend a better surgical technique for the diagnosis and treatment of such patients.
Methods:
Intraoperative fundus fluorescein angiography was performed using a customized intraoperative blue light excitation source and observed by a three-dimensional surgical observation system to explore the causes of recurrent postoperative vitreous hemorrhage.
Results:
Intraoperative three-dimensional fluorescein angiography clearly showed the complete fluorescence image of the inward growing scleral neovascularization at the pars plana vitrectomy incision site and guided the surgical treatment of intraocular laser photocoagulation of the neovascularization.
Conclusion:
Intraoperative three-dimensional fluorescein angiography has a certain role in the diagnosis and treatment of unexplained postoperative vitreous hemorrhage after pars plana vitrectomy and is a promising surgical auxiliary technology.

