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Updated: May 21, 2025

MRI and PET in Mouse Models of Myocardial Infarction
Published on: December 19, 2013
[Application study on single-channel contrast agent/tracer injection mode of positron emission tomography/magnetic
Y Q Chen1, Y T Ding1, T T Chu1
1Department of Radiology, General Hospital of Eastern Theater Command/Jinling Hospital, Medical School of Nanjing University, Nanjing 210002, China.
Abstract:
Objective: To explore the application value of the single-channel contrast agent/tracer injection mode in positron emission tomography/magnetic resonance imaging (PET/MRI) examination. Methods: A total of 65 patients who underwent PET/MRI examination in the Department of Radiology of General Hospital of Eastern Theater from June 2021 to March 2022 were prospectively enrolled as the control group (double-channel contrast/tracer injection mode), and 78 patients examined from April to May 2022 as the test group (single-channel contrast/tracer injection mode).The nursing operation time, the puncture success rate of indwelling needle, the incidence of blood extravasation, and the image quality were analyzed and compared between two groups. Results: The age of 143 patients was (53.7±16.3) years, and 90 (63.0%) were male. The control group was (54.7±17.0) years, with 43 males (66.2%). The test group was (50.8±18.5) years, with 47 males (60.3%). The nursing operation time of patients in the test group was shorter than that in the control group [3.2 (3.0, 3.3) vs 6.2 (5.4, 6.5) min]. The success rate of indwelling needle puncture in the test group was higher than that in the control group [100.0 (78/78) vs 92.3% (60/65)], and the rate of blood extravasation was lower than that in the control group [0 (0/78) vs 6.2% (4/65)] (all P<0.05). There was no statistically difference in the pass rate of PET/MRI images between two groups [94.9% (74/78) vs 98.5% (64/65), P=0.374]. Conclusion: Compared with the traditional double-channel contrast agent/tracer injection mode, the single-channel contrast agent/tracer injection mode reduces the nursing operation time and the incidence of blood extravasation, increases the success rate of indwelling needle puncture, and does not affect the image quality of PET/MRI.
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