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Updated: May 5, 2026

Assessment and Evaluation of the High Risk Neonate: The NICU Network Neurobehavioral Scale

Assessment and Evaluation of the High Risk Neonate: The NICU Network Neurobehavioral Scale

Published on: August 25, 2014

Anxiety Sensitivity in the Perinatal Period: A Scoping Review.

Martha Zimmermann¹, Allexis Mahanna¹, Elizabeth Shashkova¹

¹UMass Chan Medical School, 55 N Lake Ave, Worcester, MA 01655, USA.

Mental Health & Prevention

|March 24, 2025

Summary

Anxiety sensitivity (AS) is linked to increased perinatal mental health issues, including PTSD and anxiety, during pregnancy and postpartum. Targeting AS in interventions may improve maternal mental health outcomes.

Keywords:

Anxiety sensitivity anxiety disorders perinatal pregnancy risk factor

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Using a Murine Model of Psychosocial Stress in Pregnancy as a Translationally Relevant Paradigm for Psychiatric Disorders in Mothers and Infants

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Published on: June 13, 2021

Area of Science:

Perinatal mental health research
Psychological science
Clinical psychology

Background:

Anxiety sensitivity (AS) is a known risk factor for anxiety disorders.
Its role in perinatal mental health (pregnancy and postpartum) is less understood.
Perinatal mental health is critical due to heightened risks for anxiety, OCD, and PTSD.

Purpose of the Study:

To review the existing research on AS in perinatal populations.
To examine the relationship between AS and mental health and pregnancy-specific outcomes.
To assess the integration of AS into clinical interventions.

Main Methods:

Systematic literature search across major databases (PubMed, Scopus, PsycInfo, CINAHL).
Inclusion criteria: participants pregnant or within 1 year postpartum, and AS assessment.
Twenty studies met the inclusion criteria.

Main Results:

Positive associations found between AS and PTSD symptoms, depression, anxiety, fetal health anxiety, pregnancy anxiety, and fear of childbirth.
Mixed results were observed for AS's relationship with labor pain and anesthetic use.
Two RCTs and two case studies measured AS as an outcome.

Conclusions:

AS is significantly associated with various perinatal mental health challenges.
Future research should broaden outcome assessments and explore AS as a modifiable intervention target.
Interventions targeting AS could enhance perinatal mental health outcomes.