Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Pulmonary Tuberculosis II01:28

Pulmonary Tuberculosis II

202
Tuberculosis, or TB, is a bacterial infectious disease caused by Mycobacterium tuberculosis. While its primary impact is on the lungs, leading to pulmonary tuberculosis, it can also affect various other organs, a condition referred to as extrapulmonary tuberculosis.
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
202
Pulmonary Tuberculosis III01:31

Pulmonary Tuberculosis III

282
Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
The first classification is based on the development of the disease, and it includes the following categories:
282
Pulmonary Tuberculosis I01:29

Pulmonary Tuberculosis I

212
Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
212
Pulmonary Tuberculosis IV01:26

Pulmonary Tuberculosis IV

127
Tuberculosis, more commonly referred to as TB, is an infectious disease stemming from Mycobacterium tuberculosis. While it primarily impacts the lungs, TB can also affect other body areas. Given its severity and global impact, timely and accurate diagnosis is crucial for controlling its spread and improving patient outcomes.
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
127
Skin Diseases and Disorders01:23

Skin Diseases and Disorders

2.8K
Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
2.8K
Defense Against Bacterial Pathogens01:31

Defense Against Bacterial Pathogens

1.4K
The human immune system is a complex network of cells, tissues, and organs that work together to defend the body against bacterial infections. It consists of various immune cells, each playing a specific role in the defense mechanism.
Phagocytes
Phagocytes are the frontline soldiers of the immune system. They include neutrophils and macrophages. Neutrophils are the most abundant type of white blood cell and are quickly mobilized to the site of infection. Macrophages are larger cells that patrol...
1.4K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

High-Risk Rhabdomyosarcomas Feature a Convergent Cell State.

Cancer research·2026
Same author

Degenerative Spine.

Magnetic resonance imaging clinics of North America·2026
Same author

Global Consensus on the Management of Primary Localized Chordoma.

JAMA oncology·2026
Same author

Human rights-based mental healthcare: new developments, introducing a themed series of papers.

BJPsych open·2026
Same author

Female genital mutilation: perception of Portuguese gynecologists and obstetricians - a national survey.

The European journal of contraception & reproductive health care : the official journal of the European Society of Contraception·2026
Same author

Synthesis and Evaluation of <sup>68</sup>Ga-Labeled NT(6-13) Analogs Incorporating Non-Canonical Amino Acid Substitutions at Tyr<sup>11</sup> for Targeting NTSR1 in Various Solid Malignancies.

ACS omega·2026

Related Experiment Video

Updated: May 20, 2025

A Novel Microdissection Approach to Recovering Mycobacterium tuberculosis Specific Transcripts from Formalin Fixed Paraffin Embedded Lung Granulomas
07:42

A Novel Microdissection Approach to Recovering Mycobacterium tuberculosis Specific Transcripts from Formalin Fixed Paraffin Embedded Lung Granulomas

Published on: June 5, 2014

8.0K

A soft tissue lesion caused by Mycobacterium malmoense.

Maria Rodrigues1, Simranjeet Kaur2, Ali Al Khader3,4

  • 1Department of Radiology, Centro Hospitalar Universitário de São João, Porto, Portugal. inesreisrodrigues@gmail.com.

Skeletal Radiology
|March 24, 2025
PubMed
Summary

A rare soft tissue infection caused by Mycobacterium malmoense was identified in an elderly woman. Prompt diagnosis using advanced imaging and PCR led to effective antibiotic treatment and clinical improvement.

Keywords:
Mycobacterium malmoenseEnvironmental mycobacteriaGranulomatous inflammationSoft tissue infection

More Related Videos

Subcutaneous Infection of Methicillin Resistant Staphylococcus Aureus MRSA
12:18

Subcutaneous Infection of Methicillin Resistant Staphylococcus Aureus MRSA

Published on: February 9, 2011

22.9K
Spatial Quantification of Drugs in Pulmonary Tuberculosis Lesions by Laser Capture Microdissection Liquid Chromatography Mass Spectrometry LCM-LC/MS
09:58

Spatial Quantification of Drugs in Pulmonary Tuberculosis Lesions by Laser Capture Microdissection Liquid Chromatography Mass Spectrometry LCM-LC/MS

Published on: April 18, 2018

9.0K

Related Experiment Videos

Last Updated: May 20, 2025

A Novel Microdissection Approach to Recovering Mycobacterium tuberculosis Specific Transcripts from Formalin Fixed Paraffin Embedded Lung Granulomas
07:42

A Novel Microdissection Approach to Recovering Mycobacterium tuberculosis Specific Transcripts from Formalin Fixed Paraffin Embedded Lung Granulomas

Published on: June 5, 2014

8.0K
Subcutaneous Infection of Methicillin Resistant Staphylococcus Aureus MRSA
12:18

Subcutaneous Infection of Methicillin Resistant Staphylococcus Aureus MRSA

Published on: February 9, 2011

22.9K
Spatial Quantification of Drugs in Pulmonary Tuberculosis Lesions by Laser Capture Microdissection Liquid Chromatography Mass Spectrometry LCM-LC/MS
09:58

Spatial Quantification of Drugs in Pulmonary Tuberculosis Lesions by Laser Capture Microdissection Liquid Chromatography Mass Spectrometry LCM-LC/MS

Published on: April 18, 2018

9.0K

Area of Science:

  • Infectious Diseases
  • Microbiology
  • Dermatology

Background:

  • Soft tissue infections can be caused by various pathogens, including atypical mycobacteria.
  • Mycobacterium malmoense is an uncommon cause of infection, rarely reported in soft tissues.

Purpose of the Study:

  • To report a rare case of soft tissue infection caused by Mycobacterium malmoense.
  • To highlight the diagnostic features and successful treatment of this uncommon infection.

Main Methods:

  • Clinical presentation of a non-healing forearm lesion.
  • Diagnostic imaging including ultrasound and MRI to characterize subcutaneous nodules.
  • Histopathological examination with Ziehl-Neelsen staining and PCR for pathogen identification.

Main Results:

  • Biopsy revealed granulomatous inflammation and Ziehl-Neelsen-positive microorganisms.
  • PCR confirmed Mycobacterium malmoense as the causative agent.
  • Combined antibiotic therapy resulted in significant clinical improvement.

Conclusions:

  • Mycobacterium malmoense is an uncommon but potential cause of soft tissue infections.
  • Multimodality imaging and molecular diagnostics are crucial for accurate diagnosis.
  • Early and appropriate antibiotic treatment can effectively manage these infections.