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Updated: May 20, 2025

Simultaneous Laryngopharyngeal and Conventional Esophageal pH Monitoring
Published on: December 14, 2020
Future Directions in Managing and Treating Laryngopharyngeal Reflux Disease for Improving Patient Care
1Division of Laryngology and Broncho-esophagology, Department of Otolaryngology-Head Neck Surgery, EpiCURA Hospital, UMONS Research Institute for Health Sciences and Technology, University of Mons (UMons), Mons, Belgium; International Federation of Otorhinolaryngological Societies (IFOS), Paris, France; Department of Surgery, UMONS Research Institute for Health Sciences and Technology, University of Mons (UMons), Mons, Belgium; Department of Otorhinolaryngology and Head and Neck Surgery, Foch Hospital, Paris Saclay University, Phonetics and Phonology Laboratory (UMR 7018 CNRS, Université Sorbonne Nouvelle/Paris 3), Paris, France.
Abstract:
The etiologic mechanisms associated with the occurrence of pharyngeal reflux events, and the development of laryngopharyngeal reflux disease (LPRD) remains incompletely understood. A transversal and multidimensional approach evaluating diet, autonomic nerve dysfunction, gastroesophageal motility, microbiome alteration, and concentration of gastroduodenal enzymes in the ear, nose, and throat mucosa is needed. In addition, development of artificial intelligence software could improve selection of more personalized treatments and pretreatment to posttreatment clinical evaluations. However, the unawareness of LPRD in medicine and surgery remains the primary limiting factor for improving current LPRD knowledge and patient care.
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