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Updated: May 20, 2025

Author Spotlight: Advancing Human Brain Modulation – Optimized Protocols for Transcranial Ultrasound Stimulation Experiments
Published on: June 28, 2024
Ultrasound can deliver chemical stimulants to the skin and modulate their perception
Tor-Salve Dalsgaard1, Arpit Bhatia2, Lei Gao3
1Department of Computer Science, University of Copenhagen, Universitetsparken 1, 2100, Copenhagen, Denmark. torsalve@di.ku.dk.
Abstract:
When applied to the skin, chemical stimulants can evoke haptic sensations. However, they need to be applied continuously using paper or pads in fixed locations, limiting their usefulness as a general haptic technology. To overcome these limitations, we introduce an ultrasound-based system for the precise acoustophoresis of droplets of chemical stimulants to the skin. We show that such droplets can indeed produce distinct haptic sensations. In addition, the system can use ultrasound to stimulate the area of the skin where the stimulants have been applied. We show that this increases the perceived intensity. Taken together, these results demonstrate the promise of non-contact delivery and modulation of chemical stimulants, not only as a haptic technology but also to provide deeper insights into the interaction of the chemical and mechanical senses.
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