Multilayer Core-Sheath Structured Nickel Wire/Copper Oxide/Cobalt Oxide Composite for Highly Sensitive Non-Enzymatic...

Area of Science:

• Materials Science
• Electrochemistry
• Biomedical Engineering

Background:

• Diabetes mellitus management requires accurate, real-time blood glucose monitoring.
• Current glucose sensors face challenges in sensitivity, stability, and response time.
• Development of advanced electrode materials is crucial for improved glucose sensing.

Purpose of the Study:

• To develop a novel core-sheath microwire electrode for non-enzymatic glucose sensing.
• To investigate the electrochemical properties and performance of the NW@CuO@Co3O4 microwire.
• To evaluate the potential of this sensor for effective diabetes management.

Main Methods:

• Fabrication of a three-layer core-sheath microwire: nickel wire core, copper oxide (CuO) and cobalt oxide (Co3O4) nanowire sheath.
• Electrochemical characterization of the NW@CuO@Co3O4 microwire as an electrode.
• Performance evaluation of the non-enzymatic glucose sensor, including sensitivity, detection limit, and response time.

Main Results:

• The NW@CuO@Co3O4 microwire exhibits excellent conductivity and electrochemical catalytic activity.
• The non-enzymatic glucose sensor achieved a high sensitivity of 4053.1 μA mM⁻¹ cm⁻².
• A low detection limit of 0.89 μM and a rapid response time of less than 2 seconds were recorded.

Conclusions:

• The developed NW@CuO@Co3O4 core-sheath microwire is a promising electrode material for highly sensitive and rapid non-enzymatic glucose detection.
• This advanced sensor technology holds significant potential for improving diabetes monitoring and management.
• The unique structural design enhances electrochemical performance for glucose sensing applications.