Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

RAPIDLY GROWING CHOROIDAL METASTASIS SIMULATING IMMUNE-RELATED CHOROIDAL ADVERSE REACTION.

Retinal cases & brief reports·2026
Same author

REDUCTION OF SCLERAL THICKNESS WITH TOPICAL FLUOROMETHOLONE IN MANAGEMENT OF CHRONIC CENTRAL SEROUS CHORIORETINOPATHY COMPLICATED BY POSTERIOR CYSTOID DEGENERATION.

Retinal cases & brief reports·2025
Same author

Retinal fingerprint pattern in central serous chorioretinopathy.

Retina (Philadelphia, Pa.)·2025
Same author

Choriocapillaris perfusion assessed using optical coherence tomography angiography depends on eye color and projection artifact removal.

International ophthalmology·2025
Same author

Direct navigated focal laser photocoagulation of choroidal neovascularization in central serous chorioretinopathy.

Lasers in medical science·2025
Same author

Status of papillomacular bundle in optic disc pit associated with maculopathy.

Eye (London, England)·2025

Related Experiment Video

Updated: May 20, 2025

Retinal Vascular Reactivity as Assessed by Optical Coherence Tomography Angiography
07:23

Retinal Vascular Reactivity as Assessed by Optical Coherence Tomography Angiography

Published on: March 26, 2020

7.1K

Iris Microcirculation After Selective Laser Trabeculoplasty: A Pilot Optical Coherence Tomography Angiography Study.

Dmitrii S Maltsev1, Alexey N Kulikov1, Alina A Kazak1

  • 1Department of Ophthalmology, Military Medical Academy, St. Petersburg 194044, Russia.

Vision (Basel, Switzerland)
|March 26, 2025
PubMed
Summary

Selective laser trabeculoplasty (SLT) causes a temporary increase in iris blood vessel density, detectable by OCTA. Greater vascularity post-SLT correlates with less effective intraocular pressure reduction in glaucoma patients.

Keywords:
intraocular pressureopen-angle glaucomaoptical coherence tomography angiographyselective laser trabeculoplasty

More Related Videos

Multimodal Volumetric Retinal Imaging by Oblique Scanning Laser Ophthalmoscopy oSLO and Optical Coherence Tomography OCT
12:22

Multimodal Volumetric Retinal Imaging by Oblique Scanning Laser Ophthalmoscopy oSLO and Optical Coherence Tomography OCT

Published on: August 4, 2018

8.4K
Doppler Optical Coherence Tomography of Retinal Circulation
10:46

Doppler Optical Coherence Tomography of Retinal Circulation

Published on: September 18, 2012

18.6K

Related Experiment Videos

Last Updated: May 20, 2025

Retinal Vascular Reactivity as Assessed by Optical Coherence Tomography Angiography
07:23

Retinal Vascular Reactivity as Assessed by Optical Coherence Tomography Angiography

Published on: March 26, 2020

7.1K
Multimodal Volumetric Retinal Imaging by Oblique Scanning Laser Ophthalmoscopy oSLO and Optical Coherence Tomography OCT
12:22

Multimodal Volumetric Retinal Imaging by Oblique Scanning Laser Ophthalmoscopy oSLO and Optical Coherence Tomography OCT

Published on: August 4, 2018

8.4K
Doppler Optical Coherence Tomography of Retinal Circulation
10:46

Doppler Optical Coherence Tomography of Retinal Circulation

Published on: September 18, 2012

18.6K

Area of Science:

  • Ophthalmology
  • Glaucoma Research
  • Medical Imaging

Background:

  • Primary open-angle glaucoma (POAG) management often involves selective laser trabeculoplasty (SLT).
  • Iris microcirculation changes after SLT require further investigation.
  • Optical coherence tomography angiography (OCTA) offers a non-invasive method to assess iris vasculature.

Purpose of the Study:

  • To evaluate changes in iris microcirculation using OCTA in POAG patients post-SLT.
  • To determine the correlation between iris vascularity changes and intraocular pressure (IOP) reduction following SLT.

Main Methods:

  • Standard SLT was performed on all participants.
  • OCTA imaging of the iris was conducted pre-SLT and at one day and seven days post-SLT.
  • Iris vessel density was quantified using ImageJ software, and its correlation with IOP changes was analyzed.

Main Results:

  • Iris vessel density showed a statistically significant increase one day after SLT (p=0.002), returning to baseline by one week.
  • A significant correlation (r=0.57, p=0.002) was observed between the percentage change in iris vessel density and IOP change at three months.

Conclusions:

  • SLT induces a transient increase in iris vessel density, observable via OCTA the day after the procedure.
  • Elevated iris vascularity post-SLT is linked to a diminished IOP-lowering effect in POAG.
  • OCTA can provide insights into the vascular response to SLT and its impact on glaucoma management.