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Author Spotlight: Ex Vivo OCT-Based Multimodal Imaging of Human Donor Eyes for Research into Age-Related Macular Degeneration
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Retinal fingerprint pattern in central serous chorioretinopathy.

Maria A Burnasheva1, Dmitrii S Maltsev1, Alexei N Kulikov1

  • 1Department of Ophthalmology, Military Medical Academy, St. Petersburg, Russia ; and.

Retina (Philadelphia, Pa.)
|October 27, 2025
PubMed
Summary

Retinal fingerprint pattern (RFP) is present in 18.3% of central serous chorioretinopathy (CSCR) eyes and is linked to more subretinal fluid and better outcomes. This pattern is reversible and caused by mechanical deformation.

Keywords:
central serous chorioretinopathyoptical coherence tomography angiographyretinal fingerprint patternsubretinal fluid

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Area of Science:

  • Ophthalmology
  • Retinal Imaging
  • Choroid Diseases

Background:

  • Central serous chorioretinopathy (CSCR) is a condition affecting the retina.
  • Understanding its anatomical and clinical characteristics is crucial for patient management.

Purpose of the Study:

  • To determine the prevalence of retinal fingerprint pattern (RFP) in CSCR patients.
  • To investigate the association between RFP and disease characteristics.

Main Methods:

  • A cross-sectional retrospective study analyzed 120 CSCR eyes.
  • Retinal fingerprint pattern (RFP) presence was assessed using en face optical coherence tomography (OCT) angiography.
  • Correlations with clinical and anatomical parameters were evaluated.

Main Results:

  • Retinal fingerprint pattern (RFP) was identified in 18.3% of CSCR eyes.
  • RFP presence correlated with increased visual acuity, retinal thickness, and subretinal fluid.
  • Eyes with RFP showed more favorable subretinal fluid resolution (68.2%) compared to those without (36.8%).

Conclusions:

  • Retinal fingerprint pattern (RFP) is observable in a significant portion of CSCR eyes via en face OCT.
  • RFP is associated with greater subretinal fluid and improved anatomical outcomes.
  • RFP in CSCR is a reversible finding resulting from retinal mechanical deformation.