Related Experiment Video
Updated: Jun 18, 2026
08:04
Cytotoxic Efficacy of Photodynamic Therapy in Osteosarcoma Cells In Vitro
Published on: March 18, 2014
12.8K
Advancing Cancer Treatment and Diagnosis: A Review on Photodynamic Therapy Using OLED Technology
Rajesh Kumar Tiwari1, Rajesh Mishra1, Sanjay Kumar Sharma1
1School of Information and Communication Technology, Gautam Buddha University, Greater Noida 201312, India.
Molecules (Basel, Switzerland)
|March 27, 2025
Summary
Photodynamic therapy (PDT) uses light and photosensitizers to treat tumors with low toxicity. This review highlights organic light-emitting diodes (OLEDs) for enhanced PDT cancer treatment and diagnosis.
Area of Science:
- Oncology
- Biomedical Engineering
- Photomedicine
Background:
- Photodynamic therapy (PDT) is a non-invasive cancer treatment using light-activated photosensitizers (PSs).
- PDT offers reduced toxicity and improved healing compared to chemotherapy and radiotherapy.
- Photosensitizers also enable photodynamic diagnosis (PDD) for tumor identification.
Purpose of the Study:
- To review the clinical applications of organic light-emitting diodes (OLEDs) in photodynamic therapy for cancer.
- To explore diagnostic and therapeutic uses of OLED-based PDT across various tumor types.
- To examine the combination of PDT with near-infrared (NIR-OLEDs) for enhanced tumor targeting.
Main Methods:
- Review of clinical applications of OLEDs in PDT for cancer treatment and diagnosis.
- Exploration of specific tumor cases utilizing OLED-based PDT.
- Examination of antimicrobial PDT for diabetic foot ulcers and metronomic PDT for cancer apoptosis.
- Investigation of PDT combined with NIR-OLEDs for improved tumor targeting.
Main Results:
- OLEDs offer advancements in light delivery for consistent PDT illumination.
- PDT with OLEDs shows promise in treating various cancers, including antibiotic-resistant infections.
- Combining PDT with NIR-OLEDs may enhance tumor targeting and treatment efficacy.
Conclusions:
- OLEDs represent a significant advancement for photodynamic therapy and diagnosis in oncology.
- The integration of OLED technology in PDT can lead to more effective and targeted cancer treatments.
- Further research into NIR-OLEDs combined with PDT holds potential for superior therapeutic outcomes.
Keywords:
NIR-OLEDbiosensorsmalignant tumoursnon-invasiveorganic light emitting diodephotodynamic therapyphotosensitizerswearable OLEDsMore Related Videos
Related Concept Videos
02:49Cancer Therapies
Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
02:57Targeted Cancer Therapies
The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against specific...
There are several types of targeted therapies against specific...