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Novel ABCD1 and MTHFSD Variants in Taiwanese Bipolar Disorder: A Genetic Association Study

Yi-Guang Wang1, Chih-Chung Huang1, Ta-Chuan Yeh1

  • 1Department of Psychiatry, Tri-Service General Hospital, School of Medicine, National Defense Medical Center, Taipei 11490, Taiwan.

Medicina (Kaunas, Lithuania)
|March 27, 2025
PubMed
Summary

This study identified novel genetic variants associated with bipolar disorder (BD) in the Taiwanese Han population, including rs11156606 in the ABCD1 gene. These findings may aid in early diagnosis and targeted therapies for bipolar disorder.

Keywords:
ABCD1 geneMTHFSD geneTaiwan precision medicine initiative (TPMI)Taiwanese Han populationX-linked inheritanceassociation studybipolar disorderdisorderfatty acid metabolismgenetic association studygenetic variantsgenome-wide association study (GWAS)linkage disequilibrium (LD)minor allele frequency (MAF)populationpopulation-specific variants

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