Related Experiment Video
Updated: Aug 1, 2026

In Vitro Tumor Cell Rechallenge For Predictive Evaluation of Chimeric Antigen Receptor T Cell Antitumor Function
Published on: February 27, 2019
Chimeric antigen receptor T-cell therapy for refractory post-transplant lymphoproliferative disorder after lung
Kaleb Veit1, Tahuanty Peña2, Julia Klesney-Tait2
1University of Nebraska Medical Center, Omaha, Nebraska.
Abstract:
Chimeric antigen receptor T-cell therapy (CAR-T) has been used to treat refractory post-transplant lymphoproliferative disorder (PTLD) in solid organ transplant patients, including heart, kidney, liver, intestine, and pancreas. We report the use of CAR-T for treating refractory PTLD in a 73-year-old female who was 7 years post bilateral lung transplantation for idiopathic pulmonary fibrosis. We discuss the immunosuppression management in this patient, as well as her clinical course and outcome.

