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[Dermatitis caused by the manchineel tree].

G Guillet, R Hélenon, M H Guillet

    Annales De Dermatologie Et De Venereologie
    |January 1, 1985
    PubMed
    Summary
    This summary is machine-generated.

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    Contact dermatitis from manchineel (Hippomane mancinella L.) causes severe skin reactions. The sap

    Area of Science:

    • Dermatology
    • Toxicology
    • Botany

    Context:

    • Manchineel (Hippomane mancinella L.) exposure is prevalent along Caribbean and Central American coastlines.
    • Contact dermatitis results from sap exposure via leaves or fruit.
    • Reactions affect skin, oral, ocular, and genital mucous membranes.

    Purpose:

    • To describe the clinical presentation and potential mechanism of manchineel-induced contact dermatitis.
    • To highlight the severity of oropharyngeal and ocular lesions.
    • To introduce traditional and native remedies for managing manchineel dermatitis.

    Summary:

    • Contact dermatitis induced by manchineel sap presents with intense itching, burning, erythema, vesicles, bullae, or pustulae within an hour.
    • Severe oropharyngeal and ocular lesions can occur.

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  • The rapid onset and burn-like lesions suggest a caustic orthoergic mechanism, possibly involving phorbol esters.

    • Impact:

    • Provides a clinical description of a significant dermatological hazard in coastal regions.
    • Suggests a potential toxicological mechanism for severe contact dermatitis.
    • Offers a starting point for exploring therapeutic interventions, including traditional remedies.