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Updated: Jun 9, 2026

A Multicenter MRI Protocol for the Evaluation and Quantification of Deep Vein Thrombosis
10:26

A Multicenter MRI Protocol for the Evaluation and Quantification of Deep Vein Thrombosis

Published on: June 2, 2015

[Deep vein thrombosis in the upper extremities focusing on Paget-Schrötter syndrome]

Jærn Dalsgaard Nielsen1, Thomas Steffen Hermann1

  • 1Videncenter for Antikoagulant Behandling, Hjerteafdelingen, Københavns Universitet - Bispebjerg og Frederiksberg Hospital.

Ugeskrift for Laeger
|March 28, 2025
PubMed

Insights

Upper extremity deep vein thrombosis (UE-DVT) treatment varies by type. Anticoagulant therapy is often effective, but early surgery may improve outcomes for persistent Paget-Schrötter syndrome.

Area of Science:

  • Vascular Surgery
  • Hematology
  • Thrombosis Research

Background:

  • Upper extremity deep vein thrombosis (UE-DVT) encompasses catheter-related, cancer-associated, and primary (Paget-Schrötter syndrome) forms.
  • Each UE-DVT subtype presents distinct clinical challenges, including incidence, mortality, and treatment variability.

Purpose of the Study:

  • To review current treatment strategies for upper extremity deep vein thrombosis.
  • To evaluate the efficacy of anticoagulant therapy versus surgical intervention for UE-DVT.

Main Methods:

  • Literature review of studies on UE-DVT treatment.
  • Analysis of outcomes based on treatment modality and timing.

Main Results:

  • Anticoagulant treatment (AC) for 3-6 months generally leads to symptom resolution or mild postthrombotic syndrome.
  • Surgical intervention within 6 weeks of symptom onset may yield superior results compared to AC alone in some cases.

Conclusions:

  • Anticoagulant therapy is a primary treatment for UE-DVT.
  • Further research, including a randomized trial comparing AC alone versus AC plus early surgery, is needed for persistent symptoms.

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