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Updated: May 8, 2025

Synthetic Methodology for Asymmetric Ferrocene Derived Bio-conjugate Systems via Solid Phase Resin-based Methodology
Published on: March 12, 2015
Double-Decker Ferrocene Analogue Derived from Flexible 14π Triphyrin(2.1.1) along with an Unusual Diels-Alder Adduct:
Ishfaq A Bhat1, Subhalaxmi Panda1, Manju Sharma1
1School of Chemistry, University of Hyderabad, Prof. C. R. Rao Road, Gachibowli, Hyderabad 500046, India.
Abstract:
14π-Triphyrin(2.1.1) is used to synthesize a double-decker sandwich complex like ferrocene. The presence of only two meso-CF3 substituents provides the macrocycle with enough flexibility to undergo bowl-shaped deformation in order to complex with Fe(II) ions, forming a low-spin diamagnetic complex. Further, the Cp ligand of the metal carrier [{Fe(CO)2(Cp)}2] forms a Diels-Alder adduct with the triphyrin macrocycle at higher temperatures, which does not undergo complexation. The plausible role of factors behind the formation of sandwich complexes in [14]triphyrin(2.1.1) was explored using first-principles molecular dynamics.
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