Related Experiment Video
Updated: May 5, 2026

Tissue Collection and RNA Extraction from the Human Osteoarthritic Knee Joint
Published on: July 22, 2021
Gout: one year in review 2025
Leonardo Punzi1, Laura Scagnellato2, Paola Galozzi3
1Centre for Gout & Metabolic, Bone and Joint Diseases, Ospedale Civile SS Giovanni e Paolo, Venice, Italy.
Abstract:
The incidence of gout has increased steadily over the last decades and its management is still unsatisfactory. Growing evidence highlights the multifactorial etiology of this disease encompassing genetic predisposition, environmental stimuli and gut dysbiosis. Recent advances in biomolecular and computer sciences allowed to gain more and more genetic, epigenetic, transcriptomic, proteomics and metabolomics insights into hyperuricaemia and gout-related molecular mechanisms. Moreover, the interplay between gout and cardiovascular, metabolic and renal diseases may potentially offer novel targets for anti-inflammatory and urate-lowering therapies.This annual review aims to provide the latest updates on gout research, epidemiology, genetics, molecular mechanisms, diagnostic approach, and therapeutic advances.
Related Concept Videos
Gastritis III: Clinical Manifestations and Management
Clinical manifestations of acute gastritis
The patient with acute gastritis may have a rapid onset of symptoms, such as epigastric pain or discomfort, dyspepsia, anorexia, hiccups, or nausea and vomiting, which can last from a few hours to a few days. Erosive or hemorrhagic gastritis may cause bleeding, which may manifest as blood in vomit or as...
Chronic Pancreatitis II: Collaborative Care
Assessment:
Urinary Tract Calculi II: Pathophysiology and Clinical Manifestations
Urinary Tract Calculi III: Medical Management
Urinary Tract Calculi VI: Surgical Management
Cholecystitis
