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Updated: Jan 8, 2026

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Advocating for change-Integration of efforts across the drug discovery and development continuum

Timothy P Heffernan1, Giulio F Draetta2

  • 1Division of Therapeutics Discovery and Development, The University of Texas, MD Anderson Cancer Center, Houston, TX 77030, USA.

Cancer Cell
|March 28, 2025
PubMed

Insights

Despite advances in cancer research and drug approvals, cancer remains a leading cause of death. A transformative approach requires realigning industry and academic partnerships to better leverage innovation across the research continuum.

Area of Science:

  • Oncology
  • Biotechnology
  • Data Science

Background:

  • Significant progress in oncology drug approvals and personalized medicine has been achieved.
  • Cancer remains a primary global cause of mortality, necessitating innovative clinical care strategies.

Purpose of the Study:

  • To propose a paradigm shift in industry-academia collaborations for cancer research.
  • To align cultural and financial priorities between industry and academia.

Main Methods:

  • Leveraging pharmaceutical research and development (R&D) advancements.
  • Integrating academic innovation throughout the research continuum.

Main Results:

  • Not applicable for this proposal.

Conclusions:

  • Realigned partnerships can accelerate the translation of research into improved patient outcomes.
  • A unified approach is crucial for overcoming the persistent challenge of cancer mortality.

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