Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Glaucoma: Overview01:25

Glaucoma: Overview

1.7K
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
1.7K
Open Angle Glaucoma: Treatment01:27

Open Angle Glaucoma: Treatment

1.1K
In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
1.1K
Angle Closure Glaucoma: Treatment01:28

Angle Closure Glaucoma: Treatment

1.6K
Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
1.6K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Eyes of Africa: The Genetics of Blindness. Baseline characteristics, ocular features, and associations with glaucoma in continental Africans.

Eye (London, England)·2026
Same author

Low concentration atropine eye drops and progression of myopia in children: multicentre placebo controlled, double masked, randomised trial in the UK (CHAMP-UK).

BMJ (Clinical research ed.)·2026
Same author

Trends of blindness and visual impairment in individuals aged 70 and older.

The British journal of ophthalmology·2026
Same author

Contextual factors that affect diabetic retinopathy screening uptake at township health units in southern China: a qualitative study with service providers and users.

BMJ open·2026
Same author

PROductivity Study of Presbyopia Elimination in gaRment workers (PROSPER II): a randomised trial on the productivity impact of providing near glasses to Indian garment factory workers.

The British journal of ophthalmology·2026
Same author

Prevalence of presbyopia among social safety net beneficiaries with the cognitive, numeracy and dexterity skills required for smartphone use: a cross-sectional analysis of THRIFT RCT screening data from Kurigram, Bangladesh.

BMJ open·2026
Same journal

Treatment of genitourinary syndrome of menopause with fractional CO₂ laser versus fractional microablative radiofrequency: study protocol for a double-blind, randomised, non-inferiority trial.

Trials·2026
Same journal

TaILOR: a randomised trial to compare the clinical and cost-effectiveness of a patient-initiated follow-up (PIFU) strategy compared to standard care pathways in people with inflammatory arthritis: a study protocol.

Trials·2026
Same journal

Scaling up community-based non-communicable disease research into practice in Pokhara Metropolitan City of Nepal (SCALE-NCD) trial: study protocol for a cluster-randomized controlled trial.

Trials·2026
Same journal

EECP intervention and coronary flow reserve in chronic coronary syndrome: a protocol of a multicentre, randomised controlled study in China (ECP-Core Trial).

Trials·2026
Same journal

Impact of early tracheostomy in infratentorial lesions trial: rationale and design.

Trials·2026
Same journal

Efficacy of transcranial direct current stimulation for post-stroke urinary incontinence: study protocol for a randomized controlled trial.

Trials·2026
See all related articles

Related Experiment Video

Updated: May 1, 2026

Stereoacuity Improvement using Random-Dot Video Games
06:25

Stereoacuity Improvement using Random-Dot Video Games

Published on: January 14, 2020

15.0K

Cognitive Level Enhancement through Vision Exams and Refraction (CLEVER): study protocol for a randomised controlled

Srinivas Marmamula1,2,3,4,5, Suvarna Alladi6, Keerthana Umapathy6,7

  • 1Allen Foster Community Eye Health Research Centre, Gullapalli Pratibha Rao International Centre for Advancement of Rural Eye Care, L V Prasad Eye Institute, Hyderabad, India.

Trials
|March 29, 2025
PubMed
Summary
This summary is machine-generated.

Vision correction with spectacles may help slow cognitive decline in older adults. This study investigates if providing glasses to elderly individuals with correctable vision impairment can impact their cognitive health over three years.

Keywords:
Cognitive declineCorrectable vision lossDementiaElderlyIndiaLASI-DADRandomised controlled trial

More Related Videos

Development of a Gaze-Contingent Display Framework Designed for Perceptual and Oculomotor Research with Simulated Central Vision Loss
07:12

Development of a Gaze-Contingent Display Framework Designed for Perceptual and Oculomotor Research with Simulated Central Vision Loss

Published on: April 11, 2025

1.0K
Comparison of Agreement and Accuracy using Binocular Wavefront Optometer with Autorefractor and Phoropter
05:14

Comparison of Agreement and Accuracy using Binocular Wavefront Optometer with Autorefractor and Phoropter

Published on: September 16, 2025

820

Related Experiment Videos

Last Updated: May 1, 2026

Stereoacuity Improvement using Random-Dot Video Games
06:25

Stereoacuity Improvement using Random-Dot Video Games

Published on: January 14, 2020

15.0K
Development of a Gaze-Contingent Display Framework Designed for Perceptual and Oculomotor Research with Simulated Central Vision Loss
07:12

Development of a Gaze-Contingent Display Framework Designed for Perceptual and Oculomotor Research with Simulated Central Vision Loss

Published on: April 11, 2025

1.0K
Comparison of Agreement and Accuracy using Binocular Wavefront Optometer with Autorefractor and Phoropter
05:14

Comparison of Agreement and Accuracy using Binocular Wavefront Optometer with Autorefractor and Phoropter

Published on: September 16, 2025

820

Area of Science:

  • Ophthalmology
  • Gerontology
  • Cognitive Science

Background:

  • Observational studies link vision impairment to faster cognitive decline.
  • No randomized trials have evaluated vision correction's effect on cognitive change.
  • A three-year randomized controlled trial protocol is presented to address this gap.

Purpose of the Study:

  • To assess the impact of spectacles for distance and/or near vision correction on cognitive change.
  • To evaluate spectacles as a low-cost intervention for preventing or delaying cognitive decline in the elderly.
  • To provide evidence for public health strategies promoting cognitive health in aging populations.

Main Methods:

  • The Cognitive Level Enhancement through Vision Exams and Refraction (CLEVER) trial is a single-center, open-label, randomized controlled trial.
  • 760 participants aged ≥60 years with correctable vision impairment and normal cognition will be enrolled.
  • The primary outcome is the three-year change in the LASI-DAD global cognitive factor score.

Main Results:

  • This section is not applicable as the abstract describes a study protocol, not results.
  • The study is designed to collect data on cognitive changes over three years.
  • Results will be analyzed to determine the effect of vision correction on cognitive decline.

Conclusions:

  • The CLEVER trial is designed to determine if spectacles can prevent or delay cognitive decline.
  • Findings could inform interventions aimed at maintaining cognitive function in older adults.
  • This research addresses a critical need for evidence-based strategies in geriatric care.