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Updated: May 8, 2025

Development of Inhibitors of Protein-protein Interactions through REPLACE: Application to the Design and Development Non-ATP Competitive CDK Inhibitors
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Towards the Rational Design of Monovalent Degraders: Lessons Learnt from Cyclin K Degraders

Katie L Thomas1, Benjamin R Bellenie2, Olivia W Rossanese3

  • 1Centre for Cancer Drug Discovery, The Institute of Cancer Research, London SM2 5NG, U.K.. katie.thomas@icr.ac.uk.

Chimia
|March 29, 2025
PubMed
Abstract

Keywords:
Cyclin KMonovalent degradersTargeted protein degradation

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