Critical Care Transport of Patients With Spontaneous Coronary Artery Dissection: A Case Series
Widmac Laterion1, Michael Frakes1, Jason Cohen1
1Boston MedFlight, Bedford, MA.
Insights
Spontaneous coronary artery dissection (SCAD) predominantly affects younger women and can be a critical condition requiring advanced support. This study highlights SCAD patient demographics and critical care needs.
Area of Science:
- Cardiology
- Vascular Biology
- Critical Care Medicine
Background:
- Spontaneous coronary artery dissection (SCAD) is a tear in coronary artery walls, leading to myocardial ischemia.
- SCAD is uncommon and primarily affects young, healthy individuals, particularly women.
Purpose of the Study:
- To characterize the demographics and clinical presentation of patients with SCAD undergoing critical care transport.
- To compare SCAD transport patients to the general adult transport population.
Main Methods:
- Retrospective review of patients with SCAD diagnosis transported between April 2017 and November 2023.
- Descriptive analysis of patient characteristics, including age, sex, and peripartum status.
- Documentation of interventions such as mechanical circulatory support and vasopressors.
Main Results:
- 25 SCAD patients (77% female, median age 51) accounted for 26 transports.
- SCAD patients were significantly younger and more frequently female than the general adult transport population.
- 27% of SCAD transports involved peripartum patients; 31% required mechanical circulatory support.
Conclusions:
- SCAD patients in critical care transport are younger and more often female than other adult transport patients.
- A significant proportion of SCAD patients were peripartum and required mechanical circulatory support.
- SCAD is a high-acuity condition affecting a population not typically vulnerable to atherosclerotic coronary disease.
Objective:
Spontaneous coronary artery dissection (SCAD) refers to a naturally occurring tear or separation within the layers of the coronary artery walls. As a result, a blood-filled cavity forms within the coronary artery, obstructing blood flow to the myocardium. SCAD is an uncommon condition that predominantly affects young and healthy individuals, particularly women.
Methods:
We performed a retrospective review of patients with a known or final diagnosis of SCAD transported for the years the electronic medical record was available (April 2017-November 2023). Given the descriptive and educational nature of this case series for quality improvement, with a small number of transports of interest, comparative statistics were not performed.
Results:
We identified 30 patients with a coronary artery dissection undergoing 31 transports. Of these dissections, 2 were iatrogenic and 3 were associated with a concomitant aortic dissection, leaving 26 transports of 25 patients with SCAD. Of these patients, 20 were female (77%), and the median age was 51 (interquartile range 40.3-55.8) years. This skewed younger and more female than all adult transports, at 39.6% female with a median age of 62 (interquartile range 47-73) years. Seven (27%) of the transports involved a patient who was peripartum. In addition, 8 patients (31%) required mechanical circulatory support and 2 were on vasopressors.
Conclusion:
In a critical care transport registry, patients with SCAD were younger and more likely to be female than the general adult transport population. More than a quarter were peripartum, and 31% required mechanical circulatory support. Although rare, this is a high-acuity condition that affects a population traditionally considered to be less vulnerable to classic atherosclerotic coronary disease.
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