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Diagnosis of pericardial effusion in children: a new radiographic sign
Insights
A new chest X-ray sign, a density band near the heart, may help detect pericardial effusions in children. This finding, potentially from epicardial fat, showed 83% accuracy in a radiologist study.
Area of Science:
- Pediatric Radiology
- Cardiology
- Diagnostic Imaging
Background:
- Pericardial effusion, fluid around the heart, can be challenging to diagnose in children.
- A novel radiographic sign has been observed in anteroposterior chest films of children with pericardial effusions.
Purpose of the Study:
- To determine the incidence and diagnostic accuracy of a newly observed density band sign.
- To evaluate the sign's reliability in identifying pericardial effusions in pediatric patients.
Main Methods:
- Retrospective analysis of chest radiographs from children with and without pericardial effusions.
- Evaluation of the density band sign by independent radiologists.
- In vitro studies to investigate potential causes of the density difference.
Main Results:
- The density band sign was observed in 6 of 17 children with confirmed pericardial effusion.
- Radiologists achieved 83% sensitivity and specificity in detecting the sign in children with effusions versus controls.
- In vitro studies did not support density differences between myocardium and varying osmolarity solutions.
Conclusions:
- The newly identified density band sign may be a useful indicator of pericardial effusion in children.
- The sign is likely related to epicardial fat adjacent to pericardial fluid.
- Further research is warranted to validate this imaging finding.
Abstract:
A band of increased density paralleling the left lower border of the cardio-pericardial silhouette is seen on anteroposterior chest films in some children with pericardial effusions. To analyze the incidence and accuracy of this sign, films of children with pericardial effusions and controls were compared. Among 17 children with proved pericardial effusion, bands of density within the cardio-pericardial silhouette were seen in six films, while positive epicardial fat pad signs were seen on four. When three radiologists without experience in use of the sign evaluated radiographs of the six patients with the sign and six controls without pericardial effusion, the sign was detected in most instances in the children with effusions (specificity and sensitivity, 83%). In vitro studies of unpreserved hearts in baths of solutions of varying osmolarity failed to show detectable differences in density between myocardium and any of the solutions. We conclude that the new sign may be produced by epicardial fat adjacent to pericardial fluid.
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