Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Raman Spectroscopy: Overview01:20

Raman Spectroscopy: Overview

2.6K
The underlying principle of Raman spectroscopy is based on the interaction between light and matter, specifically molecules' inelastic scattering of photons. When a monochromatic beam of light, typically from a laser source, interacts with a sample, most scattered light has the same frequency as the incident light. This is known as Rayleigh scattering.
However, a small fraction of the scattered light exhibits a frequency shift due to the exchange of energy between the incident photons and...
2.6K
Raman Spectroscopy Instrumentation: Overview01:26

Raman Spectroscopy Instrumentation: Overview

1.8K
A conventional Raman spectrophotometer includes a laser source, a sample holding system, a wavelength selector, and a detector.
The monochromatic laser source, typically using visible or near-infrared radiation, generates a highly focused beam of light. This light interacts with the molecules of the sample, scattering some of the light. Liquid and gaseous samples are usually tested in ordinary glass capillaries, while solids can be analyzed as powders packed in capillaries or as potassium...
1.8K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Comparison of Combined Letrozole and Clomiphene Citrate With Gonadotropin Microstimulation Protocols on Fertility Outcomes.

Clinical therapeutics·2025
Same author

Effects of inter-group contact training on aging-related stereotypes among undergraduate nursing students: a randomized controlled trial.

Gerontology & geriatrics education·2025
Same author

Effect of acid modification of Biochar derived from spent mushroom substrate on the production of oyster mushroom (Pleurotus ostreatus).

Scientific reports·2025
Same author

Synthesis of 2-Aminodihydrobenzofurans through Copper-Catalyzed <i>N</i>-Alkenylation/[3,3]-Rearrangement of Aryloxyamines with Alkenyl Boronic Acids.

Organic letters·2025
Same author

Microplastics and nanoplastics in the ocular environment: Pathways, toxic effects, and future challenges.

Current research in toxicology·2025
Same author

TMEM16A inhibition suppresses melanoma metastasis.

Acta biochimica et biophysica Sinica·2025

Related Experiment Video

Updated: May 4, 2026

An Integrated Raman Spectroscopy and Mass Spectrometry Platform to Study Single-Cell Drug Uptake, Metabolism, and Effects
07:37

An Integrated Raman Spectroscopy and Mass Spectrometry Platform to Study Single-Cell Drug Uptake, Metabolism, and Effects

Published on: January 9, 2020

9.7K

Surface-enhanced Raman spectroscopy facilitates the detection of multiple metabolic modulators.

Yueyue Ma1, Na Zhou1, Zhichao Xia1

  • 1School of Science, Xihua University, Chengdu 610039, PR China.

Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy
|March 30, 2025
PubMed
Summary

This study introduces a cost-effective Surface-Enhanced Raman Scattering (SERS) method using gold nanoparticles to detect prohibited metabolic regulators in food. The technique successfully identified key substances, enhancing food safety for athletic events.

Keywords:
Gold dodecahedraMetabolic regulatorsStimulantsSurface-enhanced Raman scattering

More Related Videos

Bioorthogonal Chemical Imaging of Cell Metabolism Regulated by Aromatic Amino Acids
10:42

Bioorthogonal Chemical Imaging of Cell Metabolism Regulated by Aromatic Amino Acids

Published on: May 12, 2023

1.7K
Multimodal Optical Imaging Platform for Studying Cellular Metabolism
04:47

Multimodal Optical Imaging Platform for Studying Cellular Metabolism

Published on: June 6, 2025

1.3K

Related Experiment Videos

Last Updated: May 4, 2026

An Integrated Raman Spectroscopy and Mass Spectrometry Platform to Study Single-Cell Drug Uptake, Metabolism, and Effects
07:37

An Integrated Raman Spectroscopy and Mass Spectrometry Platform to Study Single-Cell Drug Uptake, Metabolism, and Effects

Published on: January 9, 2020

9.7K
Bioorthogonal Chemical Imaging of Cell Metabolism Regulated by Aromatic Amino Acids
10:42

Bioorthogonal Chemical Imaging of Cell Metabolism Regulated by Aromatic Amino Acids

Published on: May 12, 2023

1.7K
Multimodal Optical Imaging Platform for Studying Cellular Metabolism
04:47

Multimodal Optical Imaging Platform for Studying Cellular Metabolism

Published on: June 6, 2025

1.3K

Area of Science:

  • Analytical Chemistry
  • Spectroscopy
  • Materials Science

Background:

  • Metabolic regulators enhance athletic performance but are prohibited substances, posing challenges for fair competition.
  • Food-borne stimulants in sports pose risks, necessitating reliable detection methods.
  • Surface-Enhanced Raman Scattering (SERS) offers high sensitivity and unique spectral fingerprints for molecular detection.

Purpose of the Study:

  • To address the lack of SERS spectral data for metabolic regulators in food matrices.
  • To develop a sensitive, stable, and low-cost SERS detection technique for prohibited substances.
  • To ensure food safety in major sporting events by detecting banned metabolic regulators.

Main Methods:

  • Utilized gold dodecahedron nanoparticles as a Surface-Enhanced Raman Scattering (SERS) active substrate.
  • Successfully captured characteristic SERS peaks for six different metabolic regulatory factors.
  • Developed and validated a SERS detection technique for trimetazidine in milk samples.

Main Results:

  • Characteristic peaks of six metabolic regulators were successfully identified using the gold nanoparticle SERS substrate.
  • A stable and low-cost SERS detection method for trimetazidine in milk demonstrated a good recovery rate.
  • The developed SERS technique shows significant potential for routine food analysis.

Conclusions:

  • The proposed SERS method provides a viable solution for detecting prohibited metabolic regulators in food.
  • This technique enhances food safety surveillance, particularly for large-scale sporting events.
  • The method holds broad applicability for detecting contaminants and ensuring safety within the broader food industry.