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EXPLORING THE ROLE OF C-REACTIVE PROTEIN IN PREECLAMPSIA AMONG HYPERTENSIVE PREGNANT WOMEN
H Mohamed1, A Abdelgadir2, A Ismail3
11Clinical Scientist, Al Qasimi Women and Children Hospital, Purelab, Sharjah, United Arab Emirates.
Georgian Medical News
|March 30, 2025
Summary
High C-reactive protein (CRP) levels may predict preeclampsia (PE) in pregnant women. Monitoring CRP can identify women at higher risk for PE, especially those with a history of the condition.
Area of Science:
- Obstetrics and Gynecology
- Clinical Chemistry
- Maternal-Fetal Medicine
Background:
- Preeclampsia (PE) affects 4-5% of human pregnancies, causing significant maternal and fetal morbidity and mortality.
- PE is characterized by hypertension and proteinuria after 20 weeks gestation.
Purpose of the Study:
- To investigate the association between elevated C-reactive protein (CRP) levels and the likelihood of developing preeclampsia (PE).
Main Methods:
- Serum samples and questionnaire data were collected from 50 pregnant women with PE symptoms and 30 asymptomatic controls.
- Demographic and clinical data, including CRP levels, were analyzed.
Main Results:
- 70% of women with PE tested positive for CRP, compared to 13.3% in the control group.
- A strong correlation was observed between CRP levels and PE incidence.
- No significant effect of ethnic group on PE development was found.
Conclusions:
- C-reactive protein (CRP) is a valuable predictive marker for preeclampsia (PE).
- Monitoring CRP can aid in identifying high-risk pregnancies and potentially detecting recurrent PE.
- CRP may assist in early detection of preeclampsia.
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