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Urogenital Schistosomiasis Mimicking IgG4-RD in a Patient With HIV
Guillemette Gagey1, Didier Sorial2, Camille Rasmussen1
1Department of Clinical Immunology, Hôpital Saint Louis, AP-HP, Université Paris Cité, Paris, France.
Open Forum Infectious Diseases
|March 31, 2025
Abstract:
This article reports a case of urogenital schistosomiasis mimicking IgG4-related disease (IgG4-RD) in a 47-year-old immunocompromised man with HIV. Initially diagnosed with IgG4-RD, further biopsies revealed schistosoma eggs. Elevated IgG4 levels indicated a Th2 immune response, highlighting its complex role in antischistosomal immunity and the need for careful differential diagnosis.
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