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Related Concept Videos

Osteoclasts in Bone Remodeling01:31

Osteoclasts in Bone Remodeling

Osteoclasts are cells responsible for bone resorption and remodeling. They originate from hematopoietic progenitor cells present in the bone marrow. Numerous progenitor cells fuse to form multinucleated cells, each with 10-20 nuclei. A single osteoclast has a diameter of 150 to 200 µM. These cells have ruffled borders that break down the underlying bone tissue and release minerals such as calcium into the blood in bone resorption. Osteoclasts cling to bones with their ruffled edges during bone...
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Most bones contain compact and spongy osseous tissue, but their distribution and concentration vary based on the bone's overall function.
Compact bone, also called cortical bone, is the denser, stronger of the two types of bone tissue. It is found under the periosteum and in the diaphyses of long bones, where it provides support and protection. The microscopic structural unit of compact bone is called an osteon, or haversian system. Each osteon is composed of concentric rings of calcified...
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Bone Formation by Intramembranous Ossification

Intramembranous ossification is one of the two processes involved in the development of bones within an embryo. The flat bones of the face, most of the cranial bones, and the clavicles are formed via this process. During intramembranous ossification, the bones develop directly from sheets of undifferentiated mesenchymal connective tissue.
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Related Experiment Video

Updated: May 17, 2026

A Morphometric and Cellular Analysis Method for the Murine Mandibular Condyle
08:07

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Published on: January 11, 2018

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Mandibular Cemento‑ossifying Fibroma.

Michael Matthys1, Filip M Vanhoenacker2

  • 1AZ Sint‑Maarten, Mechelen, and UZ Brussel, Brussel, Belgium.

Journal of the Belgian Society of Radiology
|March 31, 2025
PubMed
Summary
This summary is machine-generated.

Cemento-ossifying fibroma is a benign jaw tumor presenting as a mixed radiolucent-radiopaque lesion. This condition can lead to significant root resorption and jawbone expansion.

Keywords:
Cemento‑ossifying fibromaCone beam CTMRIMandible

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Area of Science:

  • Oral pathology
  • Dental oncology
  • Maxillofacial surgery

Background:

  • Cemento-ossifying fibroma is a rare benign neoplasm originating from the periodontal ligament.
  • It predominantly affects the jawbones, particularly the mandible and maxilla.

Purpose of the Study:

  • To describe the key clinicoradiographic features of cemento-ossifying fibroma.
  • To highlight its potential to cause adjacent dental and bony structures damage.

Main Methods:

  • Review of relevant literature on cemento-ossifying fibroma.
  • Analysis of imaging characteristics (radiodensity, borders).
  • Documentation of associated pathologies like root resorption and bone expansion.

Main Results:

  • Cemento-ossifying fibroma typically exhibits a mixed radiolucent-radiopaque appearance on radiographic imaging.
  • Root resorption of adjacent teeth is a common finding.
  • Progressive bone expansion of the affected jaw segment is characteristic.

Conclusions:

  • Cemento-ossifying fibroma is a distinct benign jaw tumor requiring accurate diagnosis.
  • Early detection is crucial to manage complications such as root resorption and bone expansion.
  • Surgical management is generally curative for this benign entity.