Related Experiment Video
Updated: Jul 1, 2026
Murine Isolated Heart Model of Myocardial Stunning Associated with Cardioplegic Arrest
Published on: August 6, 2015
Cardiac complications associated with COVID-19: a single-center study from Southern Iran
Marjan Tariverdi1, Mohammadbagher Rahmati2, Maryam Mohammadian1
1Department of Pediatrics, Clinical Research Development Center of Children's Hospital, Hormozgan University of Medical Sciences, Bandar Abbas, Iran.
Insights
Cardiac abnormalities are common in children hospitalized with COVID-19, particularly those with lung involvement. Early cardiac assessments are crucial for managing pediatric COVID-19 complications.
Area of Science:
- Pediatric Cardiology
- Infectious Diseases
- Public Health
Background:
- Children typically experience milder COVID-19 symptoms than adults.
- Cardiovascular complications have been noted in pediatric COVID-19 cases.
- Understanding cardiac involvement in pediatric COVID-19 is essential.
Purpose of the Study:
- To determine the frequency of cardiac disorders in children hospitalized with COVID-19.
- To investigate the association between cardiac abnormalities and disease severity (lung involvement).
- To explore the relationship between cardiac abnormalities and patient age.
Main Methods:
- Cross-sectional study of 475 pediatric patients (1 month-14 years) hospitalized with COVID-19.
- Exclusion criteria included negative SARS-CoV-2 RT-PCR, non-COVID-19 pulmonary involvement, or pre-existing cardiac conditions.
- Cardiac assessment involved clinical evaluation, electrocardiography, echocardiography, and chest CT scans; logistic regression analyzed associations.
Main Results:
- Cardiac abnormalities were found in 35.2% of pediatric COVID-19 patients.
- Common abnormalities included dysrhythmia (20.2%), heart failure (7.6%), and abnormal echocardiography (13.1%).
- Higher odds of cardiac abnormalities correlated significantly with unilateral (3.3x) and bilateral (5.9x) lung involvement; older age showed a slight inverse association.
Conclusions:
- Cardiac abnormalities in pediatric COVID-19 are significantly linked to pulmonary involvement and disease severity.
- Routine cardiac assessments are recommended for early detection and management of complications in pediatric COVID-19.
- Findings support the importance of cardiac monitoring during COVID-19 outbreaks in children.
Background:
Children account for a small percentage of COVID-19 cases and tend to exhibit milder symptoms compared to adults. Cardiovascular involvement has been observed in pediatric COVID-19 cases. This study aimed to determine the frequency of cardiac disorders in children hospitalized with COVID-19.
Methods:
This cross-sectional study was conducted on pediatric patients admitted to Bandar Abbas Children Hospital, Iran, from March to September 2020. Patients with negative RT-PCR results for SARS-CoV-2, non-COVID-19 pulmonary involvement or pre-existing cardiovascular conditions were excluded. COVID-19 diagnostic subgroups were determined based on national guidelines. Clinical evaluations included chest CT scans to assess pulmonary involvement and cardiac assessments such as clinical symptoms, electrocardiography and echocardiography. Cardiac abnormalities were defined as clinical heart failure, dysrhythmias or abnormal echocardiography. Multivariable logistic regression was applied to analyze the associations between cardiac abnormalities, age and lung involvement, with statistical significance set at P < 0.05.
Results:
This cross-sectional study was conducted in 2020 on 475 children aged 1 month to 14 years. Among the participants, 48.4% had suspected, 30.5% had probable, and 21.1% had confirmed COVID-19. Cardiac abnormalities were identified in 35.2% of patients, including dysrhythmia (20.2%), heart failure (7.6%), and abnormal echocardiography findings (13.1%). The odds of cardiac abnormalities were 3.3 times higher in children with unilateral lung involvement and 5.9 times higher in those with bilateral lung involvement compared to those without lung involvement. Additionally, older age was associated with a 5.7% reduction in the odds of cardiac abnormalities.
Conclusions:
Cardiac abnormalities in pediatric COVID-19 patients show a significant correlation with pulmonary involvement, highlighting their link to disease severity. Routine cardiac assessments may help identify complications and guide management, especially during sporadic cases and seasonal outbreaks.
More Related Videos
08:42Cox-Maze IV Procedure Concomitant with Valvular Surgery In Situs Inversus Dextrocardia: A Single-Center Experience in China
Published on: February 11, 2022
04:43COVID-19 Seroprevalence Test for IgG Antibody Levels Among Healthy Donors Across Different Pandemic Phases in Jeddah
Published on: June 24, 2025
Related Concept Videos
01:17Ischemic Heart Disease: Overview
Atherosclerosis, the primary malefactor, orchestrates this dangerous condition. It manifests as the accumulation of fatty deposits, akin to insidious plaques, within arterial walls. As time elapses, these plaques metamorphose, hardening and...
01:26Imbalances in Cardiac Output
CHF can occur due to the failure of either side of the heart. Left-side failure leads to pulmonary congestion—the right side continues to send...
01:20Blood Studies for Cardiovascular System I: Cardiac Biomarkers
The essential diagnostic tools for detecting myocardial necrosis and monitoring individuals suspected of having acute coronary syndrome (ACS) include:
Troponins
Troponins, particularly cardiac troponins I and T, are the most precise and sensitive markers of myocardial injury. They are detectable within 4-6 hours of myocardial injury and remain...
01:17Imaging Studies for Cardiovascular System I:Echocardiography
Indications: Echocardiography is utilized to diagnose heart failure, valve disorders, and myocardial infarction. It also assesses cardiac structures' size, shape, and motion,...
01:20Imaging Studies for Cardiovascular System III: X-Ray
Definition and Purpose
An X-ray, or radiograph, is a non-invasive method that uses ionizing radiation to take images of internal structures. It is mainly used in cardiac imaging to examine the heart, lungs, and major blood vessels, aiming to identify abnormalities in the heart's size, shape, and position, such as heart failure, congenital defects, and vascular...
01:27Psychoneuroimmunology: Cardiovascular Disease
A key area of focus in PNI is the relationship between stress and coronary...