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Related Concept Videos

Bioremediation00:46

Bioremediation

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Bioremediation is the use of prokaryotes, fungi, or plants to remove pollutants from the environment. This process has been used to remove harmful toxins in groundwater as a byproduct of agricultural run-off and also to clean up oil spills.
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Drug Biotransformation: Overview01:16

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Pharmaceutical substances known as xenobiotics are predominantly lipophilic and nonionized. This enables them to permeate lipid bilayers, such as cell membranes, and interact with intracellular target receptors. Lipophilic drugs have an advantage in crossing biological barriers and reaching their intended sites of action. However, lipophilic drugs often have a restricted capacity for renal expulsion or elimination from the body. When these drugs enter the kidneys and undergo glomerular...
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Updated: May 16, 2025

Prospecting Microbial Strains for Bioremediation and Probiotics Development for Metaorganism Research and Preservation
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Pharmaceutical waste management through microbial bioremediation.

Kishore Srinivasan1, Raghu Chandrashekar Hariharapura1, Subrahmanyam Volety Mallikarjuna2

  • 1Department of Pharmaceutical Biotechnology, Manipal College of Pharmaceutical Sciences, Manipal Academy of Higher Education, Manipal, Karnataka, India.

Environmental Monitoring and Assessment
|March 31, 2025
PubMed
Summary

Pharmaceutical manufacturing creates waste harmful to ecosystems. Bioremediation using microbes offers a cost-effective solution for pharmaceutical waste, though green pharmacy approaches are also explored.

Keywords:
BioremediationGreen pharmacyMicroorganismsPharmaceutical

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Area of Science:

  • Environmental Science
  • Microbiology
  • Green Chemistry

Background:

  • Pharmaceutical products (PPs) manufacturing generates waste posing ecological risks.
  • Conventional remediation methods for pharmaceutical waste are often costly and impractical.
  • Pharmaceutical contaminants in the environment present significant health risks.

Purpose of the Study:

  • To review pharmaceutical products, their environmental presence, and health hazards.
  • To discuss microorganisms and techniques for bioremediation of pharmaceutical pollutants.
  • To explore limitations of bioremediation and sustainable green pharmacy alternatives.

Main Methods:

  • Literature review of pharmaceutical pollution and bioremediation strategies.
  • Analysis of microbial consortia and degradation techniques for pharmaceutical waste.
  • Evaluation of green pharmacy approaches for environmental impact reduction.

Main Results:

  • Bioremediation using microbial consortia shows promise as a cost-effective treatment for pharmaceutical waste.
  • Various microorganisms and techniques are effective in degrading diverse pharmaceutical pollutants.
  • Limitations exist for bioremediation, necessitating exploration of sustainable alternatives.

Conclusions:

  • Bioremediation is a viable strategy for managing pharmaceutical waste, offering environmental benefits.
  • Sustainable green pharmacy practices are crucial for minimizing the ecological impact of pharmaceutical contaminants.