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Updated: May 16, 2025

Intramucosal Inoculation of Squamous Cell Carcinoma Cells in Mice for Tumor Immune Profiling and Treatment Response Assessment
Published on: April 22, 2019
Squamous cell carcinoma associated with a history of synthetic hair implantation: Two case reports
Gregory Nicolas1, Rafael Mamoru Carneiro Tutihashi1, Nancy Emmanuel2
1Department of Plastic and Reconstructive Surgery, Hospital das Clínicas of the University of São Paulo, São Paulo, Brazil.
Abstract:
Artificial hair implantation is a popular yet controversial procedure owing to its inconclusive safety profile, with many complications such as infections, scarring, foreign body rejection, and loss of natural hair, leading to the ongoing ban on this technique in some countries. To date, three cases of squamous cell carcinoma after prosthetic fiber implantation have been reported in the literature. While insufficient data exists to establish an existing causal relationship, the significance of such a health consequence warrants further investigation and caution before applying this technique to patients. Here, we report two new cases of squamous cell carcinoma of the scalp related to synthetic hair implantation and provide a brief review of the topic.
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