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Updated: May 16, 2025

Facile Preparation of 2Z,4E-Dienamides by the Olefination of Electron-deficient Alkenes with Allyl Acetate
Published on: June 21, 2017
Visible-Light Mediated, Dual-Catalysis Enabled Allylic Difluoroalkylation via Halogen Atom Transfer
Shivani Arora1, Pragya Katiyar1, Tavinder Singh1
1Department of Chemistry, Indian Institute of Technology Kanpur, Kanpur-208016, India.
Abstract:
A visible-light-mediated protocol employing a halogen atom transfer strategy (XAT) has been developed for the synthesis of homoallylic difluorinated compounds. Employing a dual-catalysis reactivity manifold, which includes a cobaloxime catalyst, the reaction occurs without exogenous oxidant and under mild conditions. The applicability of unactivated olefins, a wide variety of halogenated precursors, and access to a diverse family of difluoromethylated molecular architectures are the highlights of this method.
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