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Resolving Water, Proteins, and Lipids from In Vivo Confocal Raman Spectra of Stratum Corneum through a Chemometric Approach
Published on: September 26, 2019
[Recalcitrant dermatophytosis]
Morten Bue Svendsen1, Karen Marie Thyssen Astvad2, Marianne Hald3
1Hudafdeling I og Allergicentret, Odense Universitetshospital.
Abstract:
In recent years, we have witnessed a rise in antifungal resistance, notably due to the emergence of Trichophyton indotineae, which is highly resistant to terbinafine. In Denmark, Trichophyton rubrum remains the most frequent causative agent. Antifungal susceptibility testing when resistance is suspected is critical for guiding treatment decisions. To prevent recalcitrant dermatophytosis from becoming endemic, it is essential to implement surveillance programs, screen close contacts, and restrict the use of topical antifungal agents.
Insights
Antifungal resistance is rising, with Trichophyton indotineae showing terbinafine resistance. Susceptibility testing and surveillance are crucial for managing recalcitrant dermatophytosis.
Area of Science:
- Mycology
- Dermatology
- Infectious Diseases
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